Skip to main content
Log in

A case of spindle cell sarcomatous change of hepatic ducts manifesting as obstructive jaundice

  • Case Reports
  • Published:
Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

Spindle cell carcinoma is a rare tumor commonly occurring in the upper aerodigestive tract. We report a 62-year-old male with spindle cell sarcomatous change located at the hepatic hilum, resulting in obstructive jaundice. The patient died after an extended resective operation. The rare disease and its histogenesis is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Appleman HD, Oberman HA. Squamous cell carcinoma of the larynx with sarcoma-like stroma: A clinicopathologic assessment of spindle cell carcinoma and “pseudosarcoma”. Am J Clin Pathol 1965:44:135–145.

    Google Scholar 

  2. Leventon GS, Evans HL. Sarcomatoid squamous cell carcinoma of the mucous membranes of the head and neck: A clinicopathologic study of 20 cases. Cancer 1981;48:994–1003.

    CAS  PubMed  Google Scholar 

  3. Zarbo RJ, Crissman JD, Venkat H, et al. Spindle-cell carcinoma of the upper aerodigestive tract mucosa: An immunohistologic and ultrastructural study of 18 biphasic tumors and comparison with seven monophasic spindle-cell tumors. Am J Surg Pathol 1986;10:741–753.

    CAS  PubMed  Google Scholar 

  4. Orsatti G, Corvalan AH, Sakurai H, Choi H-S. Polypoid adenosquamous carcinoma of the esophagus with prominent spindle cells. Arch Pathol Lab Med 1993;117:544–547.

    CAS  PubMed  Google Scholar 

  5. Evans HL, Smith JL. Spindle cell squamous carcinoma and sarcoma-like tumors of the skin: A comparative study of 38 cases. Cancer 1980;45:2687–2679.

    CAS  PubMed  Google Scholar 

  6. Gersell DJ, Katzenstein ALA. Spindle cell carcinoma of the breast. Hum Pathol 1981;12:550–561.

    CAS  PubMed  Google Scholar 

  7. Steeper TA, Piscioli F, Rosai J. Squamous cell carcinoma with sarcoma-like stroma of the female genital tract: Clinicopathological study of four cases. Cancer 1983;52:890–898.

    CAS  PubMed  Google Scholar 

  8. Matsui K, Kitagawa M, Miwa A. Lung carcinoma with spindle cell components: Sixteen cases examined by immunohistochemistry. Hum Pathol 1992;23:1289–1297.

    Article  CAS  PubMed  Google Scholar 

  9. Suster S, Huszar M, Herczeg E. Spindle cell squamous cell carcinoma of the lung: Immunocytochemical and ultrastructural study of a case. Histopathology 1987;11:871–878.

    CAS  PubMed  Google Scholar 

  10. Drlicek M, Liszka U, Machacek E, et al. Spindle cell variant of pulmonary adenocarcinoma. Pathol Res Pract 1993;189:586–590.

    CAS  PubMed  Google Scholar 

  11. Suster S, Huszar M, Herczeg E, Bubis JJ. Adenosquamous carcinoma of the gallbladder with spindle cell features. A light microscopic and immunocytochemical study of a case. Histopathology 1987;11:209–214.

    CAS  PubMed  Google Scholar 

  12. Lida Y, Tsutsumi Y. Small cell (endocrine cell) carcinoma of the gallbladder with squamous and adenocarcinomatous components. Acta Pathol Jpn 1992;42:119–125.

    Google Scholar 

  13. Burger RE, Meeler WR, Luckett PM. Squamous cell carcinoma of the common bile duct. South Med J 1987;71(2):216–219.

    Google Scholar 

  14. Fukuda T, Ohnishi Y, Sato K, et al. Transitional cell carcinoma with sarcomatous elements in the urinary tract: Six cases examined by immunochemistry. Acta Pathol Jpn 1991;41:143–149.

    CAS  PubMed  Google Scholar 

  15. DeMarco AR, Leon W, Coleman WO, et al. Pseudosarcoma of the esophagus. J Thorac Cardiovasc Surg 1965;49:188–193.

    CAS  PubMed  Google Scholar 

  16. Leifer C, Miller AS, Putong PB, Min BH. Spindle cell carcinoma of the oral mucosa: A light and electron microscopic study of apparent sarcomatous metastases to cervical lymph nodes. Cancer 1974;34:597–605.

    CAS  PubMed  Google Scholar 

  17. Pitz S, Moll R, Sturkel S et al. Expression of intermediate filament proteins in subtypes of renal cell carcinoma and in renal oncocytomas. Lab Invest 1987;56:642.

    CAS  PubMed  Google Scholar 

  18. Mietnnen M, Franssila KO, Lehto V-P, et al. Expression of intermediate proteins in thyroid gland and in thyroid tumors. Lab Invest 1983;50:262–270.

    Google Scholar 

  19. Upton MP, Hirohashi S, Tome Y, et al. Expression of vimentin in surgically resected adenocarcinoma and large cell carcinoma of lung. Am J Surg Pathol 1986;10:560–567.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yuan, CY., Lo, HW., Tseng, C.H. et al. A case of spindle cell sarcomatous change of hepatic ducts manifesting as obstructive jaundice. J Gastroenterol 30, 264–267 (1995). https://doi.org/10.1007/BF02348676

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02348676

Key words

Navigation