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Liquid chromatography separation of organic acidic compounds

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Summary

The influence of ionic compounds added to an aqueous methanol eluent on the retention behaviour of sulphonic, carboxylic acids and of phenols is demonstrated. Absolute and relative retentions can be optimized by changing the water-methanol concentrations. The optimum conditions for the separation of technical important sulphonic and carboxylic acids (dye intermediates) are shown.

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Jandera, P., Engelhardt, H. Liquid chromatography separation of organic acidic compounds. Chromatographia 13, 18–23 (1980). https://doi.org/10.1007/BF02302711

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  • DOI: https://doi.org/10.1007/BF02302711

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