Skip to main content
SpringerLink
Log in

Kompetitiver Antagonismus zwischen g-Strophanthin und Corticosteron an isolierten Streifen von Rattenaorten

  • Kurze Mitteilungen
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Corticosterone was shown to have an inhibitory effect on the contraction caused by a cardiac glycoside (g-Strophanthin = Ouabain) in isolated strips of rat aorta. It could be demonstrated that over a tenfold concentration range of Ouabain, the kinetics of this antagonism are in accord with the assumption of a competitive inhibition.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. F. Gross, Exper.2, 191 (1946).

    CAS  Google Scholar 

  2. H. Haefeli, Inang.-Diss., Basel (1954).

  3. E. Leonard, Amer. J. Physiol.189, 185 (1957).

    Article  CAS  PubMed  Google Scholar 

  4. R. F. Furchgott undS. Bhadrakom, J. Pharm. exp. Ther.108, 129 (1953).

    CAS  Google Scholar 

  5. E. J. Ariens, J. M. van Rossum andA. M. Simonis, Arzneimittel-Forsch.6, 282 (1956).

    CAS  Google Scholar 

  6. F. Sulser undW. Wilbrandt, Helv. physiol. Acta15, C 37 (1957).

  7. W. Wilbrandt, Helv. physiol. Acta16, 31 (1958).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pharmakologisches Institut der Universität Bern, Switzerland

    H. J. Schatzmann

Authors
  1. H. J. Schatzmann
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Diese Arbeit wurde ermöglicht durch ein Stipendium der « Stiftung der CIBA für naturwissenschaftliche, medizinische und technische Forschung ».

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schatzmann, H.J. Kompetitiver Antagonismus zwischen g-Strophanthin und Corticosteron an isolierten Streifen von Rattenaorten. Experientia 15, 73–74 (1959). https://doi.org/10.1007/BF02301330

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02301330

Search

Navigation