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An antineoplastic C14-labeled methylhydrazine derivative in P815 mouse leukemia. a metabolic study

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Zusammenfassung

Die endständige N-Methyl-Gruppe von 1-Methyl-C14-2-p-(isopropylcarbamoyl)benzylhydrazin-Hydrochlorid (MBH) (Ro 4-6467) erwies sich in In-vivo-Experimenten metabolisch labil, wird teilweise oxydiert und Bestandteil des Formiatpools.

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Authors and Affiliations

  1. Divisions of Experimental and Clinical Chemotherapy, Sloan-Kettering Institute for Cancer Research, USA

    W. Kreis & W. Yen

  2. Sloan-Kettering Division of Cornell University Medical College, New York, USA

    W. Kreis & W. Yen

Authors
  1. W. Kreis
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  2. W. Yen
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Kreis, W., Yen, W. An antineoplastic C14-labeled methylhydrazine derivative in P815 mouse leukemia. a metabolic study. Experientia 21, 284–286 (1965). https://doi.org/10.1007/BF02297032

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