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Experimental lathyrism: Inhibition ofβ-alanine incorporation byβ-aminopropionitrile

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  • Chimica, Biochimica, Biophysica
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Zusammenfassung

β-Aminopropionitrile verhindern wirkungsvoll die zelluläre Einlagerung vonβ-Alaninen (strukturmässig zu den Aminosäuren gehörend) in grosser Konzentrationsbreite. Aus diesem Grunde wirken Lathyrogene als Antagonisten durch Veränderung der zellulären Konzentration der Analogen. Die veränderten Produkte haben wahrscheinlich eine abnorme Funktion und die Erkrankung zur Folge.

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Authors and Affiliations

  1. School of Pharmacy, 3223 North Broad Street, 19140, Philadelphia, Pennsylvania, USA

    J. J. Aleo & A. Cammarata

  2. Temple University School of Dentistry, 19140, Philadelphia, Pennsylvania, USA

    J. J. Aleo

Authors
  1. J. J. Aleo
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  2. A. Cammarata
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Aleo, J.J., Cammarata, A. Experimental lathyrism: Inhibition ofβ-alanine incorporation byβ-aminopropionitrile. Experientia 27, 1161–1162 (1971). https://doi.org/10.1007/BF02286899

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  • DOI: https://doi.org/10.1007/BF02286899

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