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Resting energy expenditure in patients with alcoholic chronic pancreatitis

  • Pancreatic And Biliary Disorders
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Abstract

The aim of this study was to assess resting energy expenditure in patients with chronic pancreatitis; 33 patients with alcohol-related chronic pancreatitis (group 1: 13 normal weight, group 2: 20 underweight) and 11 undernourished patients without identifiable disease (group 3) were studied. Body composition was determined by bioelectric impedance analysis and energy expenditure by indirect calorimetry. The percentage of body weight occupied by fat-free mass was similar among the three groups (76.4±1.5%, 78.6±1.3% and 76.8±2.1% for groups 1, 2, and 3, respectively). The measured resting energy expenditure (REE) was higher than the predicted EE (Harris and Benedict formula and Cunningham's equation) for the underweight patients with chronic pancreatitis (group 2) (P<0.05), but not for the two other groups. According to Cunningham's equation, 65% of the group 2 patients were hypermetabolic (REE>110% of predicted EE) versus 23.1% and 20% in groups 1 and 3. When adjusted for fat free mass, REE was significantly (P<0.01) higher in group 2 (35.0±0.9 kcal/kg/24 hr) than in the other two groups (30.1±0.7 kcal/kg/24 hr and 30.8±1.4 kcal/kg/24 hr in groups 1 and 3, respectively). During chronic pancreatitis, weight loss is accompanied by hypermetabolism, which should be taken into consideration during nutritional support.

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Authors and Affiliations

  1. From the Service de Gastroentérologie et Nutrition, Centre agréé de Nutrition Parentérale à Domicile, Hôpital de l'Archet, France

    Xavier Hébuterne MD, Patrick Hastier MD, Jean-Luc Péroux MD, Nabil Zeboudj MD, Jean-Pierre Delmont MD & Patrick Rampal MD

  2. Centre d'Hépatogastroentérologie, Hôpital de Cimiez, 06202, Nice Cedex 03, France

    Xavier Hébuterne MD, Patrick Hastier MD, Jean-Luc Péroux MD, Nabil Zeboudj MD, Jean-Pierre Delmont MD & Patrick Rampal MD

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  1. Xavier Hébuterne MD
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  2. Patrick Hastier MD
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  3. Jean-Luc Péroux MD
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  4. Nabil Zeboudj MD
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  5. Jean-Pierre Delmont MD
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Hébuterne, X., Hastier, P., Péroux, JL. et al. Resting energy expenditure in patients with alcoholic chronic pancreatitis. Digest Dis Sci 41, 533–539 (1996). https://doi.org/10.1007/BF02282334

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  • DOI: https://doi.org/10.1007/BF02282334

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