Abstract
The electro-oculogram (EOG) in the 64 patients with a melanoma of the choroid or ciliary body was compared to the EOG in 11 patients with choroidal metastasis, 11 patients with choroidal naevi and 27 patients with a rhegmatogenous retinal detachment. Using the Dt and the Lp/Dt-ratio, 87.5% of the melanomas could be diagnosed correctly whereas choroidal naevus and retinal detachment were diagnosed correctly in 72.7% and 70.4% of the cases respectively. Choroidal metastases never were classified correctly. Accompanying retinal detachment, tumour volume or a break through Bruch's membrane had no influence on the EOG in the melanoma patients. An important advantage of the method is that it can be used irrespective of the condition of the other eye. Combined with ophthalmoscopy, ultrasonography and fluorescein-angiography the EOG can be an additional aid in the differential diagnosis of malignant melanoma of the choroid and ciliary body.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bohar A, Farkas A. Comparative electrophysiological observations of intraocular tumours and retinal detachment. Docum ophthalmol proc ser 1976; 10: 399–403.
François J, De Rouck A, Machildon A. Etude de l'activité bioélectrique de la rétine dans les cas de mélanome malin de la choroide guéris par photo-coagulation. Ann d'Oculist 1966; 199: 1049–67.
Graniewski-Wijnands HS, Van Lith GHM. The standing potential and its light rise in intra-ocular tumours. Docum ophthalmol proc ser 1981; 31: 106.
Jones RM, Klein R, De Venecia G, Myers FL. Abnormal electro-oculogram from eyes with a malignant melanoma of the choroid. Invest Ophthalmol Vis Sci 1981; 20: 276–9.
Markoff JI, Shakin E, Shields JA, Augsburger JJ. The electro-oculogram in eyes with malignant melanoma. Ophthalmology 1981; 88: 1122–5.
Pinckers A. Clinical electro-oculography. Acta ophthal (kbh) 1979; 57: 623–32.
Pinckers A, Hardus P, Nabbe N. The EOG in unilateral eye disease: injuries. Graefe's Arch Clin Exp Ophthalmol 1983; 220: 87–91.
Ponte F, Lauricella M. On the lack of correlation between ERG and EOG alterations in malignant melanoma of the choroid. Docum ophthalmol proc ser 1977; 13: 87–92.
Staman JA, Fitzgerald CR, Dawson WW, Barris MC, Hood CI. The EOG and choroidal malignant melanoma. Docum ophthalmol proc ser 1980; 49: 201–10.
Thijssen JM, Pinckers A, Otto AJ. A multipurpose optical system for ophthalmic electrodiagnosis. Ophthalmologica 1974; 168: 308–14.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Brink, H., Pinckers, A. & Verbeek, A. The electro-oculogram as an aid in the diagnosis of uveal melanoma. Int Ophthalmol 13, 305–309 (1989). https://doi.org/10.1007/BF02279866
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02279866