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Post anesthetic myositis in the horse associated with in vitro malignant hyperthermia susceptibility

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Abstract

Four horses with clinical and biochemical evidence of post-operative myositis following halothane anesthesia and characterized by well localized (lumbar) to generalized rigidity and pain are described. Response to Dantrolene Sodium therapy at 4 mg/kg per os was dependent upon rapidity of administration following onset. In vitro exposure of muscle to halothane and caffeine revealed increased sensitivity when compared to control horses.

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Authors and Affiliations

  1. University of Pennsylvania Veterinary School, Kennett Square, Pennsylvania, (U.S.A.)

    E. Waldron-Mease

  2. Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, (U.S.A.)

    H. Rosenberg

Authors
  1. E. Waldron-Mease
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  2. H. Rosenberg
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Waldron-Mease, E., Rosenberg, H. Post anesthetic myositis in the horse associated with in vitro malignant hyperthermia susceptibility. Vet Res Commun 3, 45–50 (1979). https://doi.org/10.1007/BF02268950

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  • DOI: https://doi.org/10.1007/BF02268950

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