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Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC

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Summary

An HPLC method for the simultaneous determination of the glucocorticoids betamethasone and dexamethasone is described. The method based on the separation of these compounds using a binary watertetrahydrofuran mobile phase and a reversed-phase Hypersil C18 column, was applied to the determination of betamethasone and dexamethasone in tablets.

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Santos-Montes, A., Gasco-López, A.I. & Izquierdo-Hornillos, R. Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC. Chromatographia 39, 539–542 (1994). https://doi.org/10.1007/BF02268276

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  • DOI: https://doi.org/10.1007/BF02268276

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