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Platelet monoamine oxidase-B activity in Parkinson's disease

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Journal of Neural Transmission - Parkinson's Disease and Dementia Section

Summary

Platelet MAO-B levels have been investigated in seventeen consecutively diagnosed and previously untreated patients with idiopathic Parkinson's disease using the non-hydroxylated catecholamine, β-phenylethylamine, as substrate. Patients with Parkinson's disease had MAO-B activity levels that were considerably higher than sex and age matched normal controls or patients with Motor neurone disease or Myasthenia gravis.

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Author notes

  1. G. B. Steventon

    Present address: School of Biochemistry, University of Birmingham, B152TT, Birmingham, UK

Authors and Affiliations

  1. Department of Neurology, Queen Elizabeth Medical Centre, B152TT, Birmingham, UK

    S. G. Sturman, M. T. E. Heafield, J. Napier & A. C. Williams

  2. School of Biochemistry, University of Birmingham, B152TT, Birmingham, UK

    R. H. Waring

Authors
  1. G. B. Steventon
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  2. S. G. Sturman
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  3. M. T. E. Heafield
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  4. R. H. Waring
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  5. J. Napier
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  6. A. C. Williams
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Steventon, G.B., Sturman, S.G., Heafield, M.T.E. et al. Platelet monoamine oxidase-B activity in Parkinson's disease. J Neural Transm Gen Sect 1, 255–261 (1989). https://doi.org/10.1007/BF02263479

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  • DOI: https://doi.org/10.1007/BF02263479

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