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The use of famotidine in the treatment of Parkinson's disease: a pilot study

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Journal of Neural Transmission - Parkinson's Disease and Dementia Section

Summary

Seven patients with idiopathic Parkinson's disease were enrolled in a ten week study to evaluate the efficacy of famotidine, an histamine H2-antagonist, in the treatment of bradyphrenia. Patients received famotidine 80 mg/day for a period of six weeks and were evaluated with neuropsychological tests. Overall, patients demonstrated improvement in variables measured. Some patients also reported an improvement in their motor symptoms.

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Author notes

  1. S. P. Molinari M.D.

    Present address: Department of Neurology, The Mount Sinai Medical Center and Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1139, 10029, New York, NY, USA

Authors and Affiliations

  1. Department of Neurology, The Mount Sinai Medical Center and Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1139, 10029, New York, NY, USA

    A. Di Rocco & M. D. Yahr

  2. Department of Psychiatry, The Mount Sinai Medical Center and Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1139, 10029, New York, NY, USA

    R. Kaminski

Authors
  1. S. P. Molinari M.D.
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  2. R. Kaminski
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  3. A. Di Rocco
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  4. M. D. Yahr
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Molinari, S.P., Kaminski, R., Di Rocco, A. et al. The use of famotidine in the treatment of Parkinson's disease: a pilot study. J Neural Transm Gen Sect 9, 243–247 (1995). https://doi.org/10.1007/BF02259665

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  • DOI: https://doi.org/10.1007/BF02259665

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