Summary
Trypanosoma vivax isolated from dairy cattle undergoing a haemorrhagic disease was inoculated into Ayrshire steers. Five of six infected animals experienced brief periods of diarrhoea and sublingual and gastro-intestinal haemorrhage. Gastro-intestinal bleeding coincided with markedly reduced numbers of thrombocytes and a high level of parasitaemia in the peripheral blood. Prothrombin times were extended and fibrinogen levels were elevated in infected animals. Plasma paracoagulation tests were positive for the presence of fibrin monomers and/or clottable early fibrin degradation products during the course of infection.
Résumé
Trypanosoma vivax isolé chez des bovins laitiers souffrant d'une maladie hémorragique a été inoculé à des bouvillons Ayrshire. 5 des 6 animaux infectés ont subi de brèves périodes de diarrhée et d'hémorragie gastrointestinales et sublinguale. Les saignements gastrointestinaux ont coïncidé avec des nombres nettement réduits des thrombocytes observés et un taux élevé de parasitémie dans le sang périphérique. Les durées pour la prothrombine étaient allongées et les taux de fibrinogène élevés chez les animaux infectés. Les tésts de paracoagulation du plasma étaient positifs quant à la présence de monomères de fibrine et/ou de produits précoces coagulables de dégradation de la fibrine au cours de l'infection.
Resumen
Se inocularon novillos Ayrshire conTrypanosoma vivax aislado de bovinos con un sindrome hemorragico. Cinco de los seis animales inoculados desarrollaron períodos cortos de diarrea y hemorragias sublinguales y gastrointestinales. Las hemorragias gastrointestinales coincidieron con trombocitopénia y paracitémia elevada en la sangre periférica. Los tiempos de protrombina fueron mayores y los niveles de fibrinógeno elevados en los animales infectados. Las pruebas de paracoagulación del plasma fueron positivas a la presencia de monómeros de fibrina y/o productos de degradación de la misma durante el curso de la enfermedad.
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Wellde, B.T., Chumo, D.A., Adoyo, M. et al. Haemorrhagic syndrome in cattle associated withtrypanosoma vivax infection. Trop Anim Health Prod 15, 95–102 (1983). https://doi.org/10.1007/BF02239803
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DOI: https://doi.org/10.1007/BF02239803