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Colonic manifestations of multiple endocrine neoplasia type 2B

Report of four cases

  • Case Reports
  • Published:
Diseases of the Colon & Rectum

Abstract

Multiple endocrine neoplasia type 2B is best known for its endocrine manifestations and typical phenotype. The gastrointestinal manifestations, however, are also an important and commonly unrecognized component of the syndrome. We present four cases that demonstrate the varied presentation of patients with colonic manifestations of multiple endocrine neoplasia type 2B. We discuss the cause, diagnostic significance, and management of the colonic disease that is a component of multiple endocrine neoplasia type 2B.

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Authors and Affiliations

  1. Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York

    James M. Woodruff M.D.

  2. Colorectal Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10021, New York, New York

    Stephen R. Grobmyer M.D.,  Jose G. Guillem M.D., Diarmuid S. O'Riordain M.D., Craig Shriver M.D. & Murray F. Brennan M.D.

Authors
  1. Stephen R. Grobmyer M.D.
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  2. Jose G. Guillem M.D.
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  3. Diarmuid S. O'Riordain M.D.
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  4. James M. Woodruff M.D.
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  5. Craig Shriver M.D.
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  6. Murray F. Brennan M.D.
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Grobmyer, S.R., Guillem, J.G., O'Riordain, D.S. et al. Colonic manifestations of multiple endocrine neoplasia type 2B. Dis Colon Rectum 42, 1216–1219 (1999). https://doi.org/10.1007/BF02238578

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