Abstract
Nonepithelial malignancies of the large bowel are rare. A new disease entity, gastrointestinal stromal tumors, has attracted attention among primary mesenchymal tumors of the gastrointestinal tract. Here we present a case of spindle-cell sarcoma of the rectum, lacking either smooth muscle cells or neural elements. Immunohistochemical findings and sequencing of the c-kit proto-oncogene diagnosed this tumor as a malignant gastrointestinal stromal tumor of the rectum.
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Kurokawa, Y., Nishisho, I., Kawahara, K. et al. Gastrointestinal stromal tumor of the rectum with activating mutation of c-kit . Dis Colon Rectum 43, 1316–1318 (2000). https://doi.org/10.1007/BF02237445
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DOI: https://doi.org/10.1007/BF02237445