Skip to main content
Log in

Free perforation in regional enteritis

  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript

Summary

1. Free perforation is a not infrequent complication of regional enteritis; 95 cases have now been recorded. It can occur in any age group and at any stage in the disease.

2. Perforations may be multiple and can occur in the jejunum and cecum as well as at the common site in the lower ileum. Drugs do not appear to play any part in their etiology; thrombosis of intramural vessels may be important.

3. The clinical picture is the classic one of perforation of the alimentary tract, with profound circulatory collapse.

4. Early surgery is essential, with either simple suture of the perforation or emergency resection when conditions are favorable.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Crohn, B. B. Acute regional ileitis. Clinical aspects and follow-up studies.New York J Med 65:641, 1965.

    PubMed  Google Scholar 

  2. Crohn, B. B. Indication for surgical intervention in regional ileitis.Arch Surg 74:305, 1957.

    Google Scholar 

  3. Arnheim, H. L., andLee, W. E. Regional ileitis with perforation, abscess and peritonitis.J Mount Sinai Hosp NY 2:61, 1935.

    Google Scholar 

  4. Cumming, R. P. Acute perforation in regional ileitis.J Roy Coll Surg Edinb 7:147, 1962.

    Google Scholar 

  5. Fischmann, M. Crohn's ileocolitis with free perforation.Prensa Med Argent 52:2116, 1965.

    PubMed  Google Scholar 

  6. Kalev, N. Case of regional enteritis complicated by free perforation.Khirurgiia (Sofia) 15:949, 1962.

    PubMed  Google Scholar 

  7. Kyle, J., andBlair, D. W. Epidemiology of regional enteritis in N.E. Scotland.Brit J Surg 52:215, 1965.

    PubMed  Google Scholar 

  8. Crismer, R., andDreze, C. Perforation into the peritoneal cavity in Crohn's disease.Arch Mal Appar Dig 53:570, 1964.

    PubMed  Google Scholar 

  9. Linden, L. W. F. Perforating acute terminal ileitis.Ann Chir Gynaec Fenn 47:362, 1958.

    PubMed  Google Scholar 

  10. Yovanovitch, M. B. Y. The place and the possibility of surgery in Crohn's disease.Arch Mal Appar Dig 50:1062, 1961.

    PubMed  Google Scholar 

  11. Armitage, G., andWilson, M. Crohn's Disease. A survey of the literature and report on 34 cases.Brit J Surg 38:182, 1950.

    PubMed  Google Scholar 

  12. Lojacono, F. A case of perforated sclero-ulcerous chronic segmental enteritis.Arch Ital Mal Appar Dig 30:56, 1963.

    Google Scholar 

  13. Rampal, M. Perforated terminal ileitis.Marseille Chir 15:129, 1963.

    Google Scholar 

  14. Homb, A. On acute regional enteritis.Acta Chir Scand 94:343, 1946.

    Google Scholar 

  15. Jackson, B. B. Chronic regional enteritis.Ann Surg 148:81, 1958.

    PubMed  Google Scholar 

  16. Daffner, J. E., andBrown, C. H. Regional enteritis. I. Clinical aspects and diagnosis in 100 patients.Ann Intern Med 49:580, 1958.

    PubMed  Google Scholar 

  17. Melassonos, J. S., andSmith, E. B. Small bowel perforation in regional enteritis secondary to administration of steroids.J Nat Med Ass 52:171, 1960.

    Google Scholar 

  18. Greene, J. M., Soronsky, S., Zackler, J., andGreene, E. L. Perforation of regional enteritis into the free peritoneal cavity.Illinois Med J 121:50, 1962.

    Google Scholar 

  19. Loblovics, I., andBesznyak, I. Perforating regional ileitis.Orv Hetil 103:1461, 1962.

    PubMed  Google Scholar 

  20. Crohn, B. B. The pathology of acute regional ileitis.Amer J Dig Dis 10:565, 1965.

    Article  PubMed  Google Scholar 

  21. Harjola, P. T., Appelqvist, R., andLilios, H. G. Small bowel perforation in Crohn's disease.Acta Chir Scand 130:143, 1965.

    PubMed  Google Scholar 

  22. Altman, A. D., Golden, D., Seidenberg, B., Kavee, D., andParker, J. G. Free perforation in regional enteritis.Amer J Dig Dis 11:658, 1966.

    Article  PubMed  Google Scholar 

  23. Robinson, K. P., andCraft, J. L. Free perforation of the small bowel due to regional enteritis.Brit J Surg 54:799, 1967.

    PubMed  Google Scholar 

  24. Lavelle, E. F. Free perforation and plasma protein depletion in regional enteritis.Brit J Surg 51:343, 1964.

    PubMed  Google Scholar 

  25. Mazal, V. Acute perforating regional ileitis.Rozhl Chir 43:726, 1964.

    PubMed  Google Scholar 

  26. Khadzhakov, A. K. Perforation of small intestine in Crohn's disease.Vestin Khir Grekov 94:122, 1965.

    Google Scholar 

  27. Krasermann, P. H. Free perforation in acute terminal ileitis.Zbl Chir 90:593, 1965.

    PubMed  Google Scholar 

  28. Gerst, P. H., Porter, M. R., andFishman, R. A. Symptomatic magnesium deficiency in surgical patients.Ann Surg 159:402, 1964.

    PubMed  Google Scholar 

  29. Krause, U. Regional enterocolitis.Svensk Lak 61:2130, 1964.

    Google Scholar 

  30. Mark, F. W. Incidental appendectomy with regional enteritis.Arch Surg (Chicago) 88:546, 1964.

    PubMed  Google Scholar 

  31. Sewel, J. H. Acute perforation of the small intestine in regional enteritis.Amer J Gastroent 47:148, 1967.

    PubMed  Google Scholar 

  32. Yamase, K. Free perforation of regional enteritis.Int Surg 45:29, 1966.

    PubMed  Google Scholar 

  33. Van Heerden, J. A., Sigler, R. M., andLynn, H. B. Regional enteritis in children: surgical aspects.Proc Mayo Clin 42:100, 1967.

    PubMed  Google Scholar 

  34. Cornell, A., andTolins, P. G. Free perforation occurring in granulomatous colitis. 3rd World Congress of Gastroenterology, Tokyo, 1966.

  35. Janowitz, H. D., Lindner, A. E., andMarshak, R. H. Granulomatous colitis: Crohn's disease of the colon.JAMA 191:825, 1965.

    PubMed  Google Scholar 

  36. Hawk, W. A., andTurnbull, R. B. Primary ulcerative disease of the colon.Gastroenterology 51:802, 1966.

    PubMed  Google Scholar 

  37. Sparberg, M., andKirsner, J. B. Long term corticosteroid therapy for regional enteritis.Amer J Dig Dis 11:865, 1966.

    Article  PubMed  Google Scholar 

  38. Barber, K. W., Waugh, J. M., Beahrs, O. H., andSauer, W. G. Indications for and results of the surgical treatment of regional enteritis.Ann Surg 156:472, 1962.

    Google Scholar 

  39. Colcock, B. P., andFortin, C. Surgical treatment of regional enteritis.Ann Surg 161:812, 1965.

    PubMed  Google Scholar 

  40. Edwards, H. Crohn's disease.J Roy Coll Surg Edinb 9:115, 1964.

    Google Scholar 

  41. Murray, I., andEdwards, H. Personal communication.

  42. Schofield, P. F. The natural history and treatment of Crohn's disease.Ann Roy Coll Surg Eng 36:258, 1965.

    PubMed  Google Scholar 

  43. Morgagni, J. B. The Seats and Causes of Diseases Investigated by Anatomy (Vol. 2), Alexander, B., Transl. Millar, Cadell, Johnson and Payne, London, 1769, p. 64.

  44. McHardy, G. Regional enteritis.Texas J Med 57:365, 1961.

    Google Scholar 

  45. Neely, J. C. Perforation in regional enteritis.JAMA 174:1680, 1960.

    PubMed  Google Scholar 

  46. Williams, W. J. Histology of Crohn's syndrome.Gut 5:510, 1964.

    Google Scholar 

  47. Lockhart-Mummery, H. E., andMorson, B. C. Crohn's disease of the large intestine.Gut 5:493, 1964.

    Google Scholar 

  48. Kyle, J. Surgery of regional enteritis.Aust New Zeal J Surg 34:116, 1964.

    PubMed  Google Scholar 

  49. Buckley, J. J., Seiden, S. P., Jiminez, F. A., andKaufman, G. Enteritis gravis. Report of three cases.Gastroenterology 42:330, 1962.

    PubMed  Google Scholar 

  50. Campbell, J. R., andKnapp, R. W. Small bowel ulceration associated with thiazide and potassium therapy.Ann Surg 163:291, 1966.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kyle, J., Caridis, T., Duncan, T. et al. Free perforation in regional enteritis. Digest Dis Sci 13, 275–283 (1968). https://doi.org/10.1007/BF02236603

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02236603

Keywords

Navigation