Abstract
We report a case of lymphoepithelioma-like carcinoma of the colon in a 62-year-old Hispanic male with multiple other tumors, including thyroid, breast, pharyngeal, and prostate carcinomas; a neurofibrosarcoma; and a meningioma. The association with Epstein-Barr virus infection and colonic lymphoepithelioma-like carcinoma was studied using immunohistochemical and polymerase chain reaction techniques.
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References
Schmincke A. Uber lympho-epitheliale Geschwulste. Beitr Pathol Anat Allg Pathol 1921;68:161–70.
Shannmugaratnam K, Sobin LH. Histological typing of upper respiratory tract tumors. International histological classification of tumors, No. 14. Geneva: World Health Organization, 1978.
Weiss L, Gaffey MJ, Shibata D. Lymphoepithelioma-like carcinoma and its relationship to Epstein-Barr virus. Am J Clin Pathol 1991;96:156–8.
Sawnson SA, Cooper PH, Mills SE, Wick MR. Lymphoepithelioma-like carcinoma of the skin. Mod Pathol 1988;1:359–65.
Butler AE, Colby TV, Weiss LM, Lombard C. Lymphoepithelioma-like carcinoma of the lung. Am J Surg Pathol 1989;13:632–9.
Kyung-Whan M, Holmquist S, Peiper SC, O'Leary TJ. Poorly differentiated adenocarcinoma with lymphoid stroma (lymphoepithelioma-like carcinomas) of stomach. Am J Clin Pathol 1991;96:219–27.
Watanabe H, Enjoji M, Imai T. Gastric carcinoma with lymphoid stroma. Cancer 1976;38:232–43.
Yuen ST, Leung SY, Chan SY.In situ detection of Epstein-Barr virus in gastric and colorectal adenocarcinomas. Am J Surg Pathol 1994;18:1158–63.
Oda K, Tamaru J, Takenouchi T,et al. Association of Epstein-Barr virus with gastric carcinoma with lymphoid stroma. Am J Pathol 1993;143:1063–71.
Amin MB, Ro JY, Lee KM,et al. Lymphoepithelioma-like carcinoma of the urinary bladder. Am J Surg Pathol 1994;18:466–73.
Onijuka M, Mitsui K, Hori M. Undifferentiated carcinoma with prominent lymphocytic infiltration (so-called lymphoepithelioma) in the trachea. Chest 1990;98:236–7.
Mills SE, Austin MB, Randall ME. Lymphoepithelioma-like carcinoma of the uterine cervix: a distinctive, un-differentiated carcinoma with inflammatory stroma. Am J Surg Pathol 1985;9:883–9.
Dietl J, Horny H-P, Kaiserling E. Lymphoepithelioma-like carcinoma of the vagina: a case report with special reference to the immunophenotype of the tumor cells and tumor-infiltrating lymphoreticular cells. Int J Gynecol Pathol 1994;13:186–9.
Saw D, Lau WH, Ho JH, Chan JK, Ng CS. Malignant lympho-epithelial lesion of the salivary gland. Hum Pathol 1986;17:914–23.
Weiss LM, Movahed LA, Butler AE,et al. Analysis of lymphoepithelioma and lymphoepithelioma-like carcinomas for Epstein-Barr viral genomes byin situ hybridization. Am J Surg Pathol 1989;13:625–31.
Pedneault L, Katz BZ. Comparison of polymerase chain reaction and standard Southern blotting for the detection of Epstein-Barr virus DNA in various biopsy specimens. J Med Virol 1993;39:33–43.
Saiki RK, Bugawan TL, Horn GT, Mullis KB, Erlich HA. Analysis of enzymatically amplified-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probe. Nature 1985;324:164–8.
Lynch H, Smyrle T, Lynch J. Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome). Int J Cancer 1996;69:28–43.
Jass JR, Smyrk TC, Stewart SM, Lane MR, Lanspa SG, Lynch HT. Pathology of hereditary non-polyposis colorectal cancer. Anticancer Res 1994;14:1631–4.
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Samaha, S., Tawfik, O., Horvat, R. et al. Lymphoepithelioma-like carcinoma of the colon. Dis Colon Rectum 41, 925–928 (1998). https://doi.org/10.1007/BF02235379
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DOI: https://doi.org/10.1007/BF02235379