Abstract
Sampson first reported a case of malignant transformation of endometriosis to adenocarcinoma in 1925. We present a case of such transformation occurring in a postmenopausal female 22 years after total abdominal hysterectomy and bilateral salpingo-oophorectomy. This case demonstrates histologic progression from endometriosis to complex hyperplasia with cytologic atypia, and ultimately to invasive endometrioid adenocarcinoma involving the rectum. Aggressive surgical extirpation of all visible colorectal endometriosis for patients with advanced disease is recommended.
Similar content being viewed by others
References
Sampson JA. Endometrial carcinoma of the ovary, arising in endometrial tissue in that organ. Arch Surg 1925;10:1–72.
Punnonen R, Klemi PJ, Nikkanen V. Postmenopausal endometriosis. Eur J Obstet Gynecol Reprod Biol 1980;11:195–200.
Henriksen E. Endometriosis. Am J Surg 1955;90:331–7.
Ranny B. Endometriosis III: complete operations: reasons, sequelae, treatment. Am J Obstet Gynecol 1971;109:1137–44.
Heaps JM, Nieberg RK, Berek JS. Malignant neoplasms arising in endometriosis. Obstet Gynecol 1990;75:1023–8.
Kurman RJ, Kaminski PF, Norris HJ. The behavior of endometrial hyperplasia: a long-term study of “untreated” hyperplasia in 170 patients. Cancer 1985;56:403–12.
Droegemueller W, Herbst AL, Mishell DR, Stenchever MA. Comprehensive gynecology. St. Louis: Mosby, 1987:953–64.
Bailey HR, Ott MT, Hartendorp P. Aggressive surgical management for advanced colorectal endometriosis. Dis Colon Rectum 1994;37:747–53.
Author information
Authors and Affiliations
About this article
Cite this article
Magtibay, P.M., Heppell, J. & Leslie, K.O. Endometriosis-associated invasive adenocarcinoma involving the rectum in a postmenopausal female. Dis Colon Rectum 44, 1530–1533 (2001). https://doi.org/10.1007/BF02234612
Issue Date:
DOI: https://doi.org/10.1007/BF02234612