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Liver injuries induced by herbal medicine, Syo-saiko-to (xiao-chai-hu-tang)

  • Liver: Infectious, Inflammatory, and Metabolic Disorders
  • Case Report
  • Published:
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References

  1. Stillman AE, Huxtable R, Consroe P, Kohnen P, Smith S: Hepatic veno-occlusive disease due to pyrrolizidine (senecio) poisoning in Arizona. Gastroenterology 73:349–352, 1977

    Google Scholar 

  2. Hyde FF: Mistletoe hepatitis. Br Med J 282:739, 1981

    Google Scholar 

  3. Rottman JN: Comfrey and liver damage. Lancet 1:944, 1981

    Google Scholar 

  4. Anderson C: Comfrey in perspective. Lancet 1:1424, 1981

    Google Scholar 

  5. Kumana CR, Ng M, Lin HJ, Ko W, Wu P-C, Todd D: Hepatic veno-occlusive disease due to toxic alkaloid in herbal tea. Lancet 1:1360–1361, 1983

    Google Scholar 

  6. Mizoguchi Y, Yoshiyasu K, Tsutsui H, Myyajima K, Sakagami Y, Tojo T, Seki M, Yamamoto Y, Morisawa S: A case of drug-induced allergic hepatitis by herbal medicine. Acta Hepatol Jpn 27:238–241, 1986

    Google Scholar 

  7. Satake I, Maeda M, Koyama W, Sakamoto S, Koizumi S, Kanayama M: A case of hepatic injury caused by an herb drug. Acta Hepatol Jpn 27:238–241, 1986

    Google Scholar 

  8. Harvey J, Colin-Jones DG: Mistletoe hepatitis. Br Med J 282:186–187, 1981

    Google Scholar 

  9. MacGregor FB, Abernethy VE, Dahabra S, Cobden I, Hayes PC: Hepatotoxicity of herbal remedies. Br Med J 199:1156–1157, 1989

    Google Scholar 

  10. Weeks GR, Proper JS: Herbal medicines—gaps in our knowledge. Aust J Hosp Pharmacol 19:155–157, 1989

    Google Scholar 

  11. Carlsson C: Herbs and hepatitis. Lancet 2:1065, 1990

    Google Scholar 

  12. Larrey D, Vial T, Pauwels A, Castot A, Biour M, David M, Michel H: Hepatitis after germander (Teucrium chamaedrys) administration: Another instance of herbal medicine hepatotoxicity. Ann Intern Med 117:129–132, 1992

    Google Scholar 

  13. Marutani K, Nishijima T, Nishiyama J, Nemoto H, Matsuo S, Matsuyama Y, Itoh S: Changes in liver test results after stopping syo-saiko-to. Acta Hepatol Jpn 31(suppl):119, 1990

    Google Scholar 

  14. Marutani K, Matsuo S, Nishijima T, Watanobe T, Ishida Y, Sasaki K, Kameda C, Itoh S: Light and electron microscopic findings in the liver of five patients with syo-saiko-to-induced hepatitis. Jpn J Gastroenterol 87:640, 1990

    Google Scholar 

  15. Itabashi M: Clinical utility of13C-aminopyrine breath test in patients with chronic liver diseases. J Saitama Med School 18:261–268, 1991

    Google Scholar 

  16. Hepner GW, Vesell ES: Quantitative assessment of hepatic function by breath analysis after oral administration of [14C]aminopyrine. Ann Intern Med 83:632–638, 1975

    Google Scholar 

  17. Stricker BHCH, Block APR, Desmet VJ: Pathology of Drug-Induced Hepatic Injury, 2nd ed. Amsterdam, Elsevier, 1992, pp 51–70

    Google Scholar 

  18. Loeper J, Deseatoire V, Letteron P, Moulis C, Degott C, Dansette P, Fau D, Pessayre D: Hepatotoxicity of germander in mice. Gastroenterology 106:464–472, 1994

    Google Scholar 

  19. Keys JD: Chinese Herbs. Their Botany, Chemistry, and Pharmacodynamics. Rutland, Vermont, Charles E. Tuttle, 1976

    Google Scholar 

  20. De Smet PAGM:Scutellaria species.In Adverse Effects of Herbal Drugs, Vol 2. PAGM De Smet, K Keller, R Hänsel (eds). Berlin, Springer-Verlag, 1993, pp 289–296

    Google Scholar 

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Itoh, S., Marutani, K., Nishijima, T. et al. Liver injuries induced by herbal medicine, Syo-saiko-to (xiao-chai-hu-tang). Digest Dis Sci 40, 1845–1848 (1995). https://doi.org/10.1007/BF02212712

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  • DOI: https://doi.org/10.1007/BF02212712

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