Skip to main content
SpringerLink
Log in

Congenital nystagmus: A clinical perspective in infancy

  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

In a series of 152 patients with congenital nystagmus, 119 had sensory nystagmus while 13 had pure motor nystagmus. The most common diagnoses in the sensory group were optic nerve hypoplasia. Leber's amaurosis, and oculocutaneous or ocular albinism. Eight of the patients in the motor group had a similarly afflicted parent. Diagnostic features in infants and preverbal children were reviewed. This study supports the continued clinical classification of congenital nystagmus into sensory and motor subtypes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Abramov I, Gordon J, Hendrickson A et al. (1982) The retina of the newborn human infant. Science 217: 265–267

    PubMed  Google Scholar 

  2. Baloh RW, Yee RD, Honrubia V (1980) Optokinetic asymmetry in patients with maldeveloped foveas. Brain Res 186: 211–216

    Article  PubMed  Google Scholar 

  3. Barricks ME, Flynn JT, Kushner BJ (1977) Paradoxical pupillary responses in congenital stationary night blindness. In: Smith JL (ed) Neuro-ophthalmology update. Masson, New York, pp 31–38

    Google Scholar 

  4. Cogan DG (1967) Congenital nystagmus. Can J Opthalmol 2: 4–10

    Google Scholar 

  5. Collewijn H (1969) Optokinetic eye movements in the rabbit: input-output relations. Vision Res 9: 117–132

    Article  PubMed  Google Scholar 

  6. Dayton GO, Jones MH (1964) Analysis of characteristics of fixation reflex in infants by use of direct current electrooculography. Neurology 14: 1152–1156

    PubMed  Google Scholar 

  7. Dayton GO, Jones MH, Steele B, Rose M (1964) Developmental study of coordinated eye movements in the human infant: an electrooculographic study of the fixation reflex in the newborn. Arch Ophthalmol 71: 871–875

    PubMed  Google Scholar 

  8. Dell'Osso LF, Flynn JR, Daroff RB (1974) Hereditary congenital nystagmus. Arch Ophthalmol 92: 366–374

    PubMed  Google Scholar 

  9. Dell'Osso LF, Daroff RB (1975) Congenital nystagmus waveforms and foveation strategies. Doc Ophthalmol 39: 155–182

    Article  PubMed  Google Scholar 

  10. Dorp DB van, Haeringen NJ van, Delleman IW (1983) Albinism: phenotype or genotype? Doc Ophthalmol 56: 183–194

    Article  PubMed  Google Scholar 

  11. Forssman B (1964) A study of congenital nystagmus. Acta Otolaryngol 57: 427–449

    PubMed  Google Scholar 

  12. Francois J (1968) Leber's congenital tapetoretinal degeneration. Int Ophthalmol Clin 8: 929–947

    PubMed  Google Scholar 

  13. Goldhammer Y (1977) Paradoxical pupillary reaction. In: Smith JL (ed) Neuro-ophthalmology update. Masson, New York, pp 39–42

    Google Scholar 

  14. Hall BD (1979) Choanal atresia and associated multiple anomalies. J Pediatrics 95: 395–398

    Google Scholar 

  15. Harcourt B (1970) Hereditary nystagmus in early childhood. J Med Genet 7: 253–256

    PubMed  Google Scholar 

  16. Hittner HM, Hirsch NJ, Kreh GM, Rudolph AJ (1979) Colobomatous micro-ophthalmia, heart disease, hearing loss and mental retardation — a syndrome. J Pediatr Ophthalmol Strabismus 16: 122–128

    PubMed  Google Scholar 

  17. Hittner HM, Borda RP, Justice J (1981) X-linked congenital stationary night blindness, myopia and tilted discs. J Pediatr Ophthalmol Strabismus 18: 15–20

    PubMed  Google Scholar 

  18. Hoyt CS, Gelbart SS (1984) Vertical nystagmus in infants with congenital ocular abnormalities. Ophthalmic Paediatr Genet 4: 155–162

    PubMed  Google Scholar 

  19. Hoyt CS, Billson F, Ouvrier R, Wise G (1978) Ocular features of Aicardi's syndrome. Arch Ophthalmol 96: 291–295

    PubMed  Google Scholar 

  20. Kestenbaum A (1961) Clinical methods of neuro-ophthalmologic examination. Grune & Stratton, New York, p 356

    Google Scholar 

  21. Merin S, Irowe H, Auerbach E, Landau J (1970) Syndrome of congenital high myopia with nyctalopia. Am J Ophthalmol 70: 541–547

    PubMed  Google Scholar 

  22. Naegele JR, Held R (1982) The postnatal development of monocular OKN in infants. Vision Res 22: 341–346

    Article  PubMed  Google Scholar 

  23. Noble KG, Carr RE (1978) Leber's congenital amaurosis. Arch Ophthalmol 96: 818–821

    PubMed  Google Scholar 

  24. Odom JV, Hoyt CS, Marg E (1981) Effect of natural deprivation and unilateral eye patching on visual acuity in infants and children. Arch Ophthalmol 99: 1412

    PubMed  Google Scholar 

  25. Oyster CW, Takahashi E, Collewijn H (1972) Direction-selection retinal ganglion cells and control of optokinetic nystagmus in the rabbit. Vision Res 12: 183–193

    Article  PubMed  Google Scholar 

  26. Pagon RA, Graham JM Jr, Zonana J, Yong S (1981) Coloboma, congenital heart disease, and choanal artresia with multiple anomalies: CHARGE association. J Pediatr 99: 223–227

    PubMed  Google Scholar 

  27. Pearce WG (1978) Congenital nystagmus: genetic and environmental causes. Can J Ophthalmol 13: 1–9

    PubMed  Google Scholar 

  28. Price MJ, Thompson HS, Judisen GF, Corbett JT (1985) Pupillary constriction to darkness. Br J Ophthalmol 69: 205–211

    PubMed  Google Scholar 

  29. Schapert-Kimmijser J, Henkes HE, van den Bosch J (1959) Amaurosis congenita (Leber). Arch Ophthalmol 61: 211–218

    Google Scholar 

  30. Skarf B, Hoyt CS (1984) Optic nerve hypoplasia in children: association with anomalies of endocrine and central nervous systems. Arch Ophthalmol 102: 62–67

    PubMed  Google Scholar 

  31. Yee RD, Wong EK, Baloh RW, Honrubia V (1976) A study of congenital nystagmus: waveforms. Neurology 26: 326–333

    PubMed  Google Scholar 

  32. Yee RD, Baloh RW, Honrubia V (1980) Study of congenital nystagmus: optokinetic nystagmus. Br J Ophthalmol 64: 926–932

    PubMed  Google Scholar 

  33. Yee RD, Baloh RW, Honrubia V (1981) Eye movement abnormalities in rod monochromacy. Ophthalmology 88: 1010–1017

    PubMed  Google Scholar 

  34. Wybar K (1972) Significance of nystagmus in suspected blindness in infancy. Isr J Med Sci 8: 1492–1495

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology, University of California School of Medicine, 94143-0344, San Francisco, CA, USA

    S. Samuel Gelbart & Creig S. Hoyt

Authors
  1. S. Samuel Gelbart
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Creig S. Hoyt
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Dedicated to Dr. G.K. von Noorden on the occasion of his 60th birthday

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gelbart, S.S., Hoyt, C.S. Congenital nystagmus: A clinical perspective in infancy. Graefe's Arch Clin Exp Ophthalmol 226, 178–180 (1988). https://doi.org/10.1007/BF02173313

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02173313

Keywords

Search

Navigation