Abstract
The ability of glaucomatous eyes to adjust to a sudden increase in intraocular pressure was investigated in nine certain glaucoma cases and in ten normal subjects. The “dynamic provoked circulatory response” (DPCR) was determined by continuously measuring the brightness of the papilla before (baseline), during, and after an abrupt artificial elevation in intraocular pressure. Following the onset of intraocular pressure elevation, the period during which the baseline brightness of the papilla persisted (latency time) was significantly (P < 0.001) shorter in glaucomatous eyes (0.64 ± 0.25 s) than in normal eyes (2.39 ± 0.68 s). This led to the suggestion that the extent to which an eye can adjust to abruptly higher intraocular pressure is measurably reduced in glaucoma. That this effect can be quantified indicates a potentially useful method for detection and follow-up of glaucoma.
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References
Christensen MS, Hoerdt-Rasmussen K, Lassen NA (1967) Cerebral vasodilatation by halothane anaesthesia in man and its potentiation by hypotension and hypercapnia. Br J Anaesth 39:927–934
Ernest JT (1974) Autoregulation of optic-disk oxygen tension. Invest Ophthalmol Vis Sci 13:101–106
Goldmann H (1981) On stereo-chronoscopy. Doc Ophthalmol 51:269–276
Greenidge K, Spaeth G (1985) Change in appearance of the optic disc associated with lowering of the intraocular pressure. Ophthalmology 92:897–903
Hendrickson PH, Robert Y, Stöckli HP (1984) Principles of photometry of the papilla. Arch Ophthalmol 102:1704–1707
MacDowall DG (1967) The effects of clinical concentrations of halothane on the blood flow and oxygen uptake of the cerebral cortex. Br J Anaesth 39:186–196
Petersdorf RG, Adams RD, Brannwald E (eds) (1983) Harrison's principles of internal medicine, 10th edn. McGraw-Hill, New York, p 1427
Robert Y (1985) Messung des Rottons der Papille. In: Robert Y (ed) Die klinischen Untersuchungsmethoden der Papille. Enke, Stuttgart, pp 110–112
Robert Y, Hendrickson PH (1984) Color appearance of the papilla in normal and glaucomatous eyes: a photopapillometric study. Arch Ophthalmol 102:1772–1775
Robert Y, Hendrickson PH (1988) Die Quantifizierung der Katarakt an der Spaltlampe. Klin Monatsbl Augenheilkd 192:406–408
Robert Y, Hendrickson PH, Best R (1986) Dynamic provoked circulatory response (DPCR) of the papilla. New Trends Ophthalmol 1:253–257
Robert Y, Hendrickson PH, Blass J, Gerber H (1986) Respiratory and circulatory influence on photopapillometry. Graefe's Arch Clin Exp Ophthalmol 224:96–100
Robert Y, Grauwiller T, Hendrickson PH, Brunner HR (1988) Die Autoregulation der Papillengefäße und ihre Verhalten unter Halothan. Klin Monatsbl Augenheilkd 192:117–121
Smith A, Wollmann H (1972) Cerebral blood flow and metabolism: effect of anesthetic drugs and techniques. Anesthesiology 36:378–400
Weinstein JM, Funsch D, Page RB, Brennen RW (1982) Optic nerve blood flow and its regulation. Invest Ophthalmol Vis Sci 23:640–645
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Presented in part at the 3rd Congress of the European Glaucoma Society, Estoril, Portugal, 23–26 May 1988
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Robert, Y., Steiner, D. & Hendrickson, P. Papillary circulation dynamics in glaucoma. Graefe's Arch Clin Exp Ophthalmol 227, 436–439 (1989). https://doi.org/10.1007/BF02172894
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DOI: https://doi.org/10.1007/BF02172894