References
Dicke KA, Spitzer G. Evaluation of the use of high-dose cytoreduction with autologous marrow rescue in various malignancies (an overview). Transplantation 1986; 41: 4.
Linch DC, Goldstone AH. Autologous bone marrow transplanation in acute leukemia (Review). Bone marrow Transplantation 1987; 2: 219.
Gale RP. Bone marrow purging: current status, future directions. Bone Marrow Transplantation 1987; Suppl 2: 107.
Bronchud MH, Scarffe JH, Thatcher N, Crowther D, Souza LM, Alton NK, Testa NG, Dexter TM. Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer. Br J Cancer 1987; 56: 809.
Morstyn G, Souza LM, Keech J, Sheridan W, Campbell L, Alton NK, Green M, Metcalf D, Fox R. Effect of granulocyte colony stimulating factor on neutropenia induced by cyctotoxic chemotherapy. Lancet 1988; 1: 667.
Gabrilove JL, Jakubowski A, Scher H, Sternberg C, Wong G, Grous J, Yagoda A, Fain K, Moore MAS, Clarkson B, Oettgen HF, Alton K, Welte K, Souza L. Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional-cell carcinoma of the urothelium. N Engl J Med 1988; 318: 1414.
Gabrilove JL, Jakubowski A, Fain K, Grous J, Scher H, Sternberg C, Yagoda A, Clarkson B, Bonilla MA, Oettgen HF, Alton K, Boone T, Altrok B, Welte K, Souza L. Phase I study of granulocyte colony-stimulating factor in patients with transitional cell carcinoma of the urothelium. J Clin Invest 1988; 82: 1454.
Antman KS, Griffin JD, Elias A, Socinski MA, Ryan L, Cannistra SA, Oette D, Whitely M, Frei E III, Schnipper LE. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression. N Engl J Med 1988; 319: 593.
Brandt SJ, Peters WP, Atwater SK, Kurtzberg J, Borowitz MJ, Jones RB, Shpall EJ, Bast RC, Jr., Gilbert CJ, Oette DH. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone marrow transplanation. N Engl J Med 1988; 318: 869.
Neumanaitis J, Singer JW, Buckner CD, Hill R, Storb R, Thomas ED, Appelbaum FR. Use of recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) in autologous marrow transplanation for lymphoid malignancies. Blood 1988; 72: 834.
Blazer BR, Kersey JH, McGlave PB, Vallera DA, Lasky LC, Haake RJ, Bostrom B, Weisdorf DR, Epstein C, Ramsay NKG.In vivo administration of recombinant human granulocyte/macrophage colony-stimulating factor in acute lymphoblastic leukemia patients receiving purged autografts. Blood 1989; 73: 849.
Neta R, Douches SD, Oppenheim JJ. Interleukin-1 is a radio-protector. J Immunol 1986; 136: 2483.
Neta R, Sztein MB, Oppenheim JJ, Gillis S, Douches SD. Thein vivo effects of interleukin-1. 1. Bone marrow cells are induced to cycle after administration of interleukin-1. J Immunol 1987; 139: 1861.
Schwartz GN, MacVittie TJ, Vigneulle RM, Patchen ML, Douches SD, Oppenheim JJ, Neta R. Enhanced hematopoietic recovery in irradiated mice pretreated with interleukin-1 (IL-1). Immunopharm and Immunotox 1987; 9: 371.
Neta R, Oppenhiem JJ, Douches SD. Interdependence of the radioprotective effects of human recombinant interleukin 1, tumor necrosis factor, granulocyte colony-stimulating factor, and murine recombinant granulocyt-macrophage colony-stimulating factor. J Immunol 1988; 140: 108.
Castelli MP, Block PL, Schneider M, Pennington R, Abe F, Talmadge JE. Protective, resotative, and therapeutic properties of recombinant human IL-1 in rodent models. J Immunol 1988; 140: 3830.
Moore MAS, Warren DJ. Synergy of interleukin-1 and granulocyte-macrophage colony-stimulating factor:in vivo stimulation of stem-cell recovery and hematopoietic regeneration following 5-Fluorouracil treatment of mice. Proc Natl Acad Sci USA 1987; 84: 7134.
Neta R, Oppenheim JJ, Douches SD, Giclas PC, Imbra RJ, Karin M. Radioprotection with IL-1. Comparison with other cytokines. In: Cinader B, Miller RG, eds. Progress of Immunology, VI. New York: Academic Press, 1986; 900–9.
Rosenthal M, Hodgson GS, Bradley TR. Organization of hematopoietic stem cells: The generation-age hypothesis. Cell Tissue Kinet 1979; 12: 17.
Bradley TR, Hodgson GS. Detection of primitive macrophage progenitor cells in bone marrow. Blood 1979; 54: 1446.
Bartelmez SH, Stanley E. Synergism between hemopoietic growth factors (HGFs) detected by their effects on cells bearing receptors for lineage specific HGF: Assay of hemopoietin 2. J Cell Physiol 1985; 122: 370.
Bartelmez SH, Sacca R, Stanley E. Lineage specific receptors used to identify a growth factor for developementally early hemopoietic cells: Assay of hemopoietin 1. J Cell Physiol 1985; 122: 362.
Stanley ER, Bartocci A, Partinkin D, Rosendaal M, Bradley TR. Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1. Cell 1986; 45: 667.
Michizuki DY, Eisenman JR, Conlon PJ, Larsen AD, Tushinski RJ. Interleukin-1 regulates hematopoietic activity, a role previously ascribed to hemopoietin 1. Proc Natl Acad Sci USA 1987; 84: 5267.
Zsebo KM, Wypych J, Yuschenkoff VN, Lu H, Hunt P, Dukess PP, Langley KE. Effects of hematopoietin-1 and interleukin 1 activities on early hematopoietic cells of the bone marrow. Blood 1988; 71: 962.
McNiece I, Kriegher T, Quesenberry P. Stimulation of primitive progenitor cells by factors produced by 5637 cells: comparison to interleukin-1 alpha. (abstract). J Cell Biochem 1989; Suppl 13c: 16.
Moore MAS, Warren DJ, Souza LM. Synergistic interaction between interleukin-1 and CSF's in hematopoiesis. In: Gale RP, Golde DW, eds. Recent Advances in Leukemia and Lymphoma. New York: Alan R. Liss, 1986: 445–56.
Bartelmez SH, Bradley TR, Bertoncello I, Mochizuki DY, Tushinski RJ, Stanley E, Hapel AJ, Young IG, Kriegler AB, Hodgson GS. Interleukin 1 plus interleukin 3 plus colony-stimulating factor 1 are essential for clonal proliferation of primitive myeloid bone marrow cells. Exptl Hematol 1989; 17: 240.
Moreb J, Zucali JR, Gross MA, Dinarello CA. Influence of interleukin 1 on human marrow blast progenitor cellsin vitro. In: Powanda MC, Oppenheim JJ, Kluger MJ, Dinarello CA. eds. Monokines and Non-lymphocytic Cytokines. New York: Alan R. Liss, 1988: 297–300.
Jubinsky PT, Stanley ER. Purification of hematopoietin 1: a multinlineage hemopoietic growth factor. Proc Natl Acad Sci USA 1985; 82: 2764.
Sharkis SJ, Santos GW, Colvin M. Elimination of acute myelogenous leukemic cells from marrow and tumor suspensions in the rat with 4-hydroperoxycyclophosphamide. Blood 1980; 55: 521.
Kaizer H, Stuart RK, Brookmeyer R, Beschorner WE, Braine HG, Burns WH, Fuller DJ, Korbling M, Mangan KF, Sarai R, Sensenbrenner LL, Shadduck RK, Shende AC, Tutschka PJ, Yeager AM, Zinkham WH, Santos GW. Autologous bone marrow transplanation in acute leukemia: A phase I study ofin vitro treatment of marrow with 4-hydroperoxycyclophosphamide to purge tumor cells. Blood 1985; 65: 1504.
Yeager AM, Kaizer H, Santos GW, Sarai R, Colvin MO, Stuart RK, Braine HG, Burke RJ, Ambinder RF, Burns WH, Fuller DJ, Davis JM, Karp JE, Stratford WM, Rowley SD, Sensenbrenner LL, Vogelsang GB, Wingard JR. Autologous bone marrow transplanation in patients with acute non-lymphocytic leukemia, usingex vivo marrow treatment with 5-hydroperoxycyclophosphamide. N Engl J Med 1986; 315: 141.
Kohn FR, Sladek NE. Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines. Biochem Pharmacol 1985; 34: 3465.
Sladek NE, Landamer GJ. Restoration of sensitivity to oxazaphosphorines by inhibitors of aldehyde dehydrogenase acitivity in cultured oxazaphosphorine-resistant L1210 and cross-linking agent-resistant P388 cell lines. Cancer Res 1985; 45: 1549.
Rowley SD, Colvin MO, Stuart RK. Human multilineage progenitor cell sensitivity to 4-hydroperoxycyclophosphamide. Exptl Hematol 1985; 13: 295.
Moreb J, Zucali JR, Gross MA, Weiner RS. Protective effects of IL-1 on human hematopoietic progenitor cells treatedin vitro with 4-hydroperoxycyclophosphamide. J Immun 1989; 142: 1937.
Monette FC, Signounas G. Growth of murine multipotent stem cells in a simple “serum free” culture system: Role of interleukin-3, erythropoietin, and hemin. Exptl Hematol 1988; 16: 250.
Williams DE, Hangoc G, Cooper S, Boswell HS, Shadduck RK, Gillis SK, Waheed S, Urdal D, Broxmeyer HE. The effects of purified recombinant murine interleukin-3 and/or purified natural murine CSF-1in vivo on the proliferation of murine high- and low-proliferatioe potential colony-forming cells: Demonstration ofin vivo synergism. Blood 1987; 70: 401.
Leary AG, Yang Y-C, Clark SC, Gasson JC, Golde DW, Ogawa M. Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: Comparison with recombinant human granulocyte-macrophage colony-stimulating factor. Blood 1987; 70: 1343.
Koike K, Stanley E, Ihle JN, Ogawa M. Macrophage colony formation supported by purified CSF-1 and/or interleukin 3 in serum free culture: Evidence for hierarchial difference in macrophage colony-forming cells. Blood 1986; 67: 859.
Sieff CA, Niemeyer CM, Nathan DG, Ekem SC, Bieber FR, Yang Y-C, Wong G, Clark SC. Stimulation of human hematopoietic colony formation by recombinant gibbon multi-colony-stimulating factor or interleukin 3. J Clin Invest 1987; 80: 818.
Moreb J, Zucali JR, Weiner RS. The role of interleukin 3 and interleukin 6 in the protection from 4-hydroperoxy-cyclophosphamide and the proliferation of early hematopoietic progenitor cells. Exptl Hematol 1989; in press.
Van Damme J, Cayphas S, Opdenakker G, Bilian A, Van Snich J. Interleukin 1 and poly (r1), poly (rC) induce production of a hybridoma growth factor by fibroblasts. Eur J Immunol 1987; 17: 1.
Kohase M, May LT, Tamm I, Vilcek J, Sehgal PB. A cytokine network in human diploid fibroblasts: Interactions of B interferons, tumor necrosis factor, platelet-derived growth factor, and interleukin-1. Mol Cell Biol 1987; 7: 273.
Billiau A. Interferon B2 as a promoter of growth and differentiation of B cells. Immunology Today 1987; 8: 84.
Yang YC, Tsai S, Wong GG, Clark SC. Interleukin 1 regulation of hematopoietic growth factor production by human stromal fibroblasts. J Cell Physiol 1988; 134: 292.
Neta R, Vogel SN, Sipe JD, Wong GG, Nordan RP. Comparison ofin vivo effects of human recombinant IL-1 and human recombinant IL-6 in mice. Lymphokine Res 1988; 7: 403.
Slordal L, Warren DJ, Moore MA. Effects of recombinant murine tumor necrosis factor on hemopoietic reconstitution in sublethally irradiated mice. J Immunol1989; 142: 833.
Le J, Vilcek J. Biology of Disease. Tumor necrosis factor and interleukin-1: Cytokines with multiple overlapping biological activities. Lab Invest 1987; 56: 234.
Dinarello CA, Ikejima T, Warner SJC, Oreneole SF, Lonnemann G, Cannon JG, Libby P. Interleukin 1 induces interleukin 1. 1. Induction of circulating interleukin 1 in rabbitsin vivo and in human mononuclear cellsin vitro. J Immunol 1987; 139: 1902.
Ikebuchi K, Wong GG, Clark SC, Ihle JN, Hirai Y, Ogawa M. Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci USA 1987; 84: 9035.
Philip R, Epstein LB. Tumor necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, gamma interferon and interleukin-1. Nature 1986; 323: 86.
Zucali JR, Dinarello CA, Oblon DJ, Gross MA, Anderson L, Weiner RS. Interleukin-1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2. J Clin Invest 1986; 77: 1857.
Zucali JR, Broxmeyer HE, Dinarello CA, Gross MA, Weiner RS. Regulation of early human hematopoietic (BFU-E and CU-GEMM) progenitor cellsin vitro by interelukin 1-induced fibroblast-conditioned medium. Blood 1987; 69: 33.
Bagby GC, Dinarello CA, Wallace P, Wagner C, Hefeneider S, McCall E. Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells. J Clin Invest 1987; 78: 1316.
Sieff CA, Tsai S, Faller DV. Interleukin-1 induces cultured human endothelial cell production of granulocyte-macrophage colony-stimulating factor. J Clin Invest 1987; 79: 48.
Rennick D, Yang G, Gemmell L, Lee F. Control of hemopoiesis by a bone marrow stromal cell clone: lipopolysaccharide and interleukin-l-inducible production of colony-stimulating factors. Blood 1987; 69: 682.
Broudy JC, Kaushansky K, Harlan JM, Adamson JW. Interleukin-1 stimulates human endothelial cells to produce granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor. J Immunol 1987; 139: 464.
Curt GA, Clendennin N, Chabner BA. Drug resistance in cancer. Cancer Treat Rep 1984; 68: 87.
Sahovic EA, Colvin M, Hilton J, Ogawa M. Role of aldehyde dehydrogenase in survival of progenitors for murine blast cell colonies after treatment with 4-hydroperoxycyclophosphamidein vitro. Cancer Res 1988; 48: 1223.
Zucali JR, Moreb J, Weiner RS, Gross MA, Green V, Duncan B. Fractionation of early hematopoietic progenitor cells from human bone marrow by elutriation centrifugation and immunomagnetic beads. (abstract). Exptl Hematol 1988; 16: 437.
Onozaki K, Matsushima K, Aggarwal BB, Oppenheim JJ. Human interleukin-1 is a cytocidal factor for several tumor cell lines. J Immunol 1985; 135: 3692.
Lovett D, Kozan B, Hadam M, Resch K, Gemsa D. Macrophage cytotoxicity: interleukin 1 as a mediator of tumor cytostasis. J Immunol 1986; 136: 340.
Nakmura S, Nakata N, Kashimoto S, Yoshida H, Yamada M. Antitumor effect of recombinant human interleukin-1 alpha against murine syngeneic tumors. Jpn J Cancer Res 1986; 77: 767.
Moreb J, Zucali JR, Gross MA, Weiner RS. Preincubation with interleukin 1 increases the cytotoxicity of 4-hydroperoxycyclophosphamide toward leukemic cells while protecting normal human hematopoietic progenitor cells. (abstract). Blood 1988; 72: 398a.
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Moreb, J., Zucali, J.R. Role of interleukin-1 in 4-hydroperoxycyclophosphamide toxicity to bone marrow progenitor cells: A review. Biotherapy 1, 273–280 (1989). https://doi.org/10.1007/BF02171003
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DOI: https://doi.org/10.1007/BF02171003