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Der Einfluß des adrenocorticotropen Hormons auf die Thrombozytenzahl

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Summary

A single dose of ACTH of 25 mg or four divided doses of 6 mg each over a period of 24 hours causes an increase in thrombocytes, which give a curve showing a more marked peak than the daily fluctuations of the platelet level. The platelet increase is parallel with the one of total leucocytes, whereas the eosinophiles and lymphocytes decrease at the same time. These changes were not observed in a patient with Addison's disease, treated similarly.

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Authors and Affiliations

  1. Medizinische Universitätsklinik Zürich, Switzerland

    F. Koller & H. Zollikofer

Authors
  1. F. Koller
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  2. H. Zollikofer
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Additional information

Das ACTH (Cortrophin) wurde uns in liebenswürdiger Weise von Herrn Dr.M. Tausk, Direktor der N. V. Organon-Oss (Holland) zur Verfügung gestellt, wofür wir ihm zu bestem Dank verpflichtet sind.

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Koller, F., Zollikofer, H. Der Einfluß des adrenocorticotropen Hormons auf die Thrombozytenzahl. Experientia 6, 299–300 (1950). https://doi.org/10.1007/BF02170904

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