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Über eine Strahlenschutzwirkung von Apresolin und C. 5864-Su (2-Octahydro-1-azocynil-äthyl-guanidin)

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Summary

Mice exposed to a lethal total-body X-irradiation were partly protected by comparatively small doses of 1-hydrazinophthalazine (Apresoline®), and even smaller ones of [2-(octahydro-1-azocinyl)-ethyl]-guanidine (C. 5864-Su, guanethidine), administered prophylactically. On the other hand, only C. 5864-Su and reserpine, but not Apresoline, afforded protection against organic peroxide intoxication.

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  1. Forschungslaboratorien der CIBA Aktiengesellschaft, Pharmazeutische Abteilung, Basel

    R. Jaques & R. Meier

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  1. R. Jaques
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  2. R. Meier
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Jaques, R., Meier, R. Über eine Strahlenschutzwirkung von Apresolin und C. 5864-Su (2-Octahydro-1-azocynil-äthyl-guanidin). Experientia 16, 75–76 (1960). https://doi.org/10.1007/BF02170269

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