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Activation analysis study on subcellular distribution of trace elements in human brain tumor

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Abstract

The concentrations of up to 11 elements in subcellular fractions of human brain (normal and malignant tumor) have been determined by a combination of gradient centrifugation and INAA methods. Samples of human brain were homogenized in a glass homogenizer tube, the homogenate was separated into nuclei, mitochondrial, myelin, synaptosome fractions, and these fractions were then analyzed using the INAA method. The discussions of elemental subcellular distributions in human brain malignant tumor are presented in this paper.

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Authors and Affiliations

  1. Shanghai Institute of Nuclear Research, Academia Sinica, P.O.Box 800-204, 201800, Shanghai, P.R. China

    Zheng Jian, Zhuang Guisun, Wang Yongji & Dong Mo

  2. Department of Pathology and Neurology, Huashan Hospital, P.R. China

    Zhang Fulin

Authors
  1. Zheng Jian
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  2. Zhuang Guisun
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  3. Wang Yongji
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  4. Dong Mo
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  5. Zhang Fulin
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Jian, Z., Guisun, Z., Yongji, W. et al. Activation analysis study on subcellular distribution of trace elements in human brain tumor. Journal of Radioanalytical and Nuclear Chemistry Letters 166, 97–107 (1992). https://doi.org/10.1007/BF02169576

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  • DOI: https://doi.org/10.1007/BF02169576

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