Abstract
Bilateral serous retinal detachments are rare complications of thrombotic thrombocytopenic purpura (TTP). We report the case of a 28-year-old woman with chronic relapsing TTP with bilateral serous retinal detachments, which resolved after prompt aggressive medical therapy. Unlike serveral previous reports, the retinal detachments in our patient were unrelated to systemic hypertension.
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Ambrosi EL, Ultmann JE (1966) Thrombotic thrombocytopenia: report of 16 cases and review of the literature. Medicine 45:139–159
Benson DO, Fitzgibbons JF, Goodnight SH (1980) The visual system in thrombotic thrombocytopenic purpura. Arch Ophthalmol 12:413–417
Clinicopathological conference (1963). N Engl J Med 269:1195–1203
Clinicopathological conference (1964). Mayo Clin Proc 39:792–805
Cogan DG (1975) Ocular involvement in disseminated intravascular coagulation. Arch Ophthalmol 93:1–8
Fastenberg DM, Fetenhour CL, Choromokos E, Shock DE (1980) Choroidal vascular changes in toxemia of pregnancy. Am J Ophthalmol 89:362–368
Gaudric A, Coscas G, Bird AC (1982) Choroidal ischemia. Am J Ophthalmol 94:489–498
Gaudric A, Sterkers M, Coscas G (1987) Retinal detachment after choroidal ischemia. Am J Ophthalmol 104:364–372
Jaben SL, Norton EWD (1982) Exudative retinal detachment in Wegener's granulomatosis: case report. Ann Ophthalmol 14:717–720
Lambert SR, High KA, Cotlier E, Benz EJ (1985) Serous retinal detachments in thrombotic thrombocytopenic purpura. Arch Ophthalmol 103:1172–1174
Lewellen DR, Singerman LJ (1980) Thrombotic thrombocytopenic purpura with optic disk neovascularization, vitreous hemorrhage, retinal detachment, and optic atrophy. Am J Ophthalmol 89:840–844
Machemer R (1984) The importance of fluid absorption, traction, intraocular currents, and chorioretinal scars in the therapy of rhegmatogenous retinal detachments. Am J Ophthalmol 98:681–693
Moschcowitz E (1925) An acute febrile pleiochromic anemia with hyaline thrombosis of terminal arterioles and capillaries. Arch Int Med 36:89–93
O'Brien JL, Sibley WA (1958) Neurologic manifestations of thrombotic thrombocytopenic purpura. Neurology 8:55–64
Percival SPB (1970) Ocular findings in thrombotic thrombocytopenic purpura (Moschcowitz's disease). Br J Ophthalmol 54:73–78
Percival SPB (1970) The eye and Moschcowitz's disease (thrombotic thrombocytopenic purpura). A review of 182 cases. Trans Ophthalmol Soc UK 30:375–382
Ridolfi RL, Bell WR (1981) Thrombotic thrombocytopenic purpura: report of 25 cases and review of the literature. Medicine 60:413–428
Snir M, Cohen S, Ben-Sira I, Buckman G (1985) Retinal manifestations of thrombotic thrombocytopenic purpura (TTP) following use of contraceptive treatment. Ann Ophthalmol 17:109–112
Stefani FH, Brandt F, Pielsticker K (1978) Periarteritis nodosa and thrombotic thrombocytopenic purpura with serous retinal detachment in siblings. Br J Ophthalmol 62:402–407
Stern WH, Ernest JT (1974) Microsphere occlusion of the choriocapillaris in rhesus monkeys. Am J Ophthalmol 78:438–448
Venecia G de, Jampol LM (1984) The eye in accelerated hypertension. II. Localized serous detachments of the retina in patients. Arch Ophthalmol 102:68–73
Weiter JJ, Ernest JT (1974) Anatomy of the choroidal vasculature. Am J Ophthalmol 78:583–590
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Wyszynski, R.E., Frank, K.E. & Grossniklaus, H.E. Bilateral retinal detachments in thrombotic thrombocytopenic purpura. Graefe's Arch Clin Exp Ophthalmol 226, 501–504 (1988). https://doi.org/10.1007/BF02169195
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DOI: https://doi.org/10.1007/BF02169195