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Spezifische Schädigung von Netzhautelementen durch Jodazetat

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Summary

The effect of iodoacetate (20 mg/kg sc. 32 mg/kg) on the structures of the retina was investigated in rabbits. The left, and then the right, eye was tested after a period of 22 and 38 days respectively following the intravenous administration of the substance. At both times the electroretinogram was completely extinguished. Histological examination revealed selective destruction of rods and cones, whereas bipolars and ganglion cells were more resistent.

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Literatur

  1. W. K. Noell, J. cell. comp. Physiol.37, 283 (1951).

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Authors and Affiliations

  1. Physiologisches Institut der Universität Wien, Austria

    G. Schubert & H. Bornschein

Authors
  1. G. Schubert
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  2. H. Bornschein
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Schubert, G., Bornschein, H. Spezifische Schädigung von Netzhautelementen durch Jodazetat. Experientia 7, 461–462 (1951). https://doi.org/10.1007/BF02168694

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  • DOI: https://doi.org/10.1007/BF02168694

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