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Catalase inhibition: A possible mechanism for the production of heinz bodies in erythrocytes

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Zusammenfassung

Experimentell wird gezeigt, dass Heinzsche Körper durch niedere Konzentrationen von Natriumazid und 2:4-dichlorphenol gebildet werden. Diese Substanzen hemmen Katalase stark, und es wird angenommen, dass die Katalasehemmung die erste Stufe beim Abbau von Hämoglobin und anderer Zellbestandteile ist. Dies führt zur Bildung von Heinzschen Körpern.

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Authors and Affiliations

  1. Physical Chemistry Laboratory, Oxford and Clinical Pathology Laboratory, The Radcliffe Infirmary, Oxford

    S. Brenner & A. C. Allison

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  1. S. Brenner
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  2. A. C. Allison
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Overseas Science Research Scholar of the Royal Commission for the Exhibition of 1851.

Staines Medical Research Fellow of Exeter College, in receipt of a grant from the Medical Research Council.

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Brenner, S., Allison, A.C. Catalase inhibition: A possible mechanism for the production of heinz bodies in erythrocytes. Experientia 9, 381–384 (1953). https://doi.org/10.1007/BF02167644

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