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Productionin vitro of melanin-like pigmentation by cells of the intestinal mucosa

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Zusammenfassung

Gefrierschnitte von frischem oder formalin-fixiertem Dünndarm verschiedener Tierarten werden in teilweise autoxydierten, 2 × 10−3-molaren Lösungen von Dopamin, Dopa, Adrenalin, Hydroxytryptamin und verwandten Verbindungen bei pH=8 inkubiert. Gewisse Zellen der tunica propria der Schleimhaut zeigen dann nach relativ kurzer Zeit eine zum Teil sehr starke granuläre Pigmentierung ihres Zytoplasmas.

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References

  1. B. Bloch andP. Ryhiner, Z. exp. Med.5, 177 (1917).

    Article  Google Scholar 

  2. B. Bloch,Handbuch für Haut- und Geschlechtskrankheiten, vol. 1, part. 1 (Springer, Berlin 1927).

    Google Scholar 

  3. T. B. Fitzpatrick, S. W. Becker, A. B. Lerner, andH. Montgomery, Science112, 223 (1950).

    Article  CAS  Google Scholar 

  4. A. B. Lerner, Amer. J. Med.19, 902 (1955).

    Article  CAS  Google Scholar 

  5. H. S. Mason, Nature177, 79 (1956).

    Article  CAS  Google Scholar 

  6. H. S. Mason, Adv. Enzymol.16, 105 (1955).

    CAS  Google Scholar 

  7. C. Monder, J. N. Williams, andH. A. Waisman, Arch. Biochem. Biophys.72, 255 (1957).

    Article  CAS  Google Scholar 

  8. R. I. T. Cromartie andJ. Harley-Mason, Biochem. J.66, 713 (1957).

    Article  CAS  Google Scholar 

  9. G. B. Koelle andJ. S. Friedenwald, Arch. Biochem. Biophys.32, 370 (1951).

    Article  CAS  Google Scholar 

  10. A. G. E. Pearse,Histochemistry, Theoretical and Applied (Little Brown, Boston 1953).

    Google Scholar 

  11. R. D. Lillie,Histopathologic Technic and Practical Histochemistry, 2nd ed. (Blakiston, New York 1954).

    Google Scholar 

  12. P. Van Duijn, J. Histochem. Cytochem.1, 143 (1953); Acta physiol. pharmacol. Neerland5, 413, 428 (1957).

    Article  Google Scholar 

  13. B. Bloch andF. Schaaf, Klin. Wschr.11, 11 (1932).

    Google Scholar 

  14. P. Mulzer andH. Schmalfuss, Med. Klinik27, 1099 (1931).

    Google Scholar 

  15. P. Van Duijn, Acta physiol. pharmacol. Neerland5, 413, 428 (1957).

    Google Scholar 

  16. H. L. Bockus, J. H. Willard, andJ. Bank, J. Amer. med. Ass.101, 1 (1933).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pharmacology, University of Zürich, Switzerland

    H. Langemann

  2. Department of Physiology and Pharmacology, Graduate School of Medicine, University of Pennsylvania, USA

    G. B. Koelle

Authors
  1. H. Langemann
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  2. G. B. Koelle
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Additional information

This investigation was supported by research grants [B-282 (C3 and C4)] from the National Institute of Neurological Diseases and Blindness, National Institutes of Health, Public Health Service

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Langemann, H., Koelle, G.B. Productionin vitro of melanin-like pigmentation by cells of the intestinal mucosa. Experientia 14, 303–306 (1958). https://doi.org/10.1007/BF02167015

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