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L'acide thymonucléique polymérisé, principe paraissant susceptible de déterminer la spécificité sérologique et l'équipement enzymatique des bactéries. Signification pour la biochimie de l'hérédité

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Summary

Interactions between two types of bacteria can produce either inhibition of the growth of one of these bacteria or transformation of their biochemical or antigenic properties. Authors have shown and studied one case of induction of a new serological specificity and a new enzymic equipment in aBacterium coli. This induction was produced through a substance liberated, during autolysis, by an otherBacterium coli. Active principle is a thymonucleic acid which, maybe, results from a solubilisation of chromosomes of the inductor bacteria. Hypothesis appears likely.

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References

  1. A. Boivin, L. Corre etY. Lehoult, C. R. Soc. Biol.136, 98, 257 et 432 (1942);137, 42, 138, 410 et 714 (1943).

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  2. Bull. Acad. Méd.127, 95, 125 et 162 (1943).

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  3. Rev. Immunol.7, 97 (1942).

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  4. Des phénomènes du même ordre ont été rencontrés parLisbonne, Nègre, Roman etSeigneurin (Ann. Inst. Pasteur61, 822 [1938]) au cours de leurs ingénieuses expériences de «parabiose» (culture de deux bactéries dans deux portions d'un même milieu séparées par une membrane de collodion infranchissable pour les germes, mais perméable à leurs produits métaboliques).

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  5. J. exp. Med.79, 137 (1944).

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Authors and Affiliations

  1. Institut Pasteur, Paris - Garches

    André Boivin, Albert Delaunay, Roger Vendrely & Yvonne Lehoult

Authors
  1. André Boivin
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  2. Albert Delaunay
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  3. Roger Vendrely
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  4. Yvonne Lehoult
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Boivin, A., Delaunay, A., Vendrely, R. et al. L'acide thymonucléique polymérisé, principe paraissant susceptible de déterminer la spécificité sérologique et l'équipement enzymatique des bactéries. Signification pour la biochimie de l'hérédité. Experientia 1, 334–335 (1945). https://doi.org/10.1007/BF02163813

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  • DOI: https://doi.org/10.1007/BF02163813

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