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Preparation of samarium-153-EDTMP and determination of its radiochemical purity using paper chromatography

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Abstract

Samarium-153-ethylenediaminetetramethylenephosphonate (153Sm-EDTMP) has been used to palliate pain resulting from bone cancer. This paper describes the preparation of153SmCl3 from irradiated natural samarium and the ability of153Sm to complex with EDTMP in liquid and in freeze-dried forms. The evaluation of radiolabeled EDTMP was done by paper chromatography. A rapid evaluation of free153SmCl3 and153Sm-EDTMP was developed using a miniaturized chromatographic system.

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References

  1. A.J.B. McEwan,Eur. J. Nucl. Med., 20 (1993) 1.

    PubMed  Google Scholar 

  2. W.F. Goeckeler, D.E. Troutner, W.A. Volkert, B. Edwards, J. Simon, D.W. Wilson,Nucl. Med. Biol., 13 (1986) 479.

    Google Scholar 

  3. W.A. Volkert, W.F. Goeckeler, G.J. Ehrhardt, A.R. ketring,J. Nucl. Med., 32 (1991) 174.

    PubMed  Google Scholar 

  4. W.F. Goeckeler, B. Edwards, W.A. Volkert, R.A. Holmes, J. Simon, D. Wilson,J. Nucl. Med., 28 (1987) 495.

    PubMed  Google Scholar 

  5. Sh.Zh. Luo, M.F. Pu, J. Quao, Zh.L. Liu, Ch.Y. Zhang, P.J. Zhao, Y.B. Fu, H.F. Deng,J. Radioanal. Nucl. Chem. Articles, 160 (1992) 443.

    Article  Google Scholar 

  6. J.R. Garlich, S.A. Baugman, J. Simon, K. McMillan, A.R. Ketring, W.A. Volkert, W.F. Goeckeler, D.E. Troutner,J. Label. Compds, Radiopharm., XXIII (1986) 1341.

    Google Scholar 

  7. A. Singh, R.A. Holmes, M. Farhangi, W.A. Volkert, A. Williams, L.M. Stringham, A.R. Ketring,J. Nucl. Med., 30 (1989) 1814.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Instituto de Pesquisas Energéticas e Nucleares, Comissão Nacional de Energia Nuclear/SP, Pinheiros, Caixa Postal 11049, 05422-970, São Paulo, SP, Brazil

    Haroldo Taurian Gasiglia & Helena Okada

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  1. Haroldo Taurian Gasiglia
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  2. Helena Okada
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Gasiglia, H.T., Okada, H. Preparation of samarium-153-EDTMP and determination of its radiochemical purity using paper chromatography. Journal of Radioanalytical and Nuclear Chemistry Letters 199, 295–304 (1995). https://doi.org/10.1007/BF02162455

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  • DOI: https://doi.org/10.1007/BF02162455

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