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Der Einfluss von Chlorpromazin auf die oxydative Phosphorylierung von Tumormitochondrien

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Summary

High concentrations of chlorpromazine cause a considerable decrease of the oxidative phosphorylation of tumor mitochondria and rat liver mitochondria. Regarding preliminary experimental and clinical investigations, we assume that malignant tumors can be sensitised to cytotoxic substances and ionising radiations impairing their energy metabolism by uncoupling the oxidative phosphorylation.

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Literatur

  1. W. Lührs, E. Heise undG. Bacigalupo, Nature,183, 1534 (1959).

    Article  PubMed  Google Scholar 

  2. G. Bacigalupo, W. Lührs undE. Heise, Acta biol. med. german.2, 455 (1959).

    CAS  PubMed  Google Scholar 

  3. W. Lührs, 7. Deutsch. Krebskongress, April 1959 in Berlin (im Druck).

  4. H. B. Collier undG. M. Allenby, Can. J. med. Sci.30, 443 (1952).

    CAS  PubMed  Google Scholar 

  5. L. G. Abood, Proc. Soc. exp. Biol. Med., N.Y.88, 688 (1955).

    Article  CAS  Google Scholar 

  6. M. Berger, H. J. Strecker undH. Waelsch, Nature177, 1234 (1956).

    Article  CAS  PubMed  Google Scholar 

  7. H. Löw, Biochim. biophys. Acta32, 11 (1959).

    Article  PubMed  Google Scholar 

  8. H. Löw, Biochim. biophys. Acta32, 1 (1959).

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Abteilung für experimentelle und klinische Chemo-Therapie der Geschwulstklinik des Institutes für Medizin und Biologie der Deutschen Akademie der Wissenschaften in Berlin-Buch, Germany

    W. Lührs, G. Bacigalupo, B. Kadenbach & E. Heise

Authors
  1. W. Lührs
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  2. G. Bacigalupo
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  3. B. Kadenbach
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  4. E. Heise
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Lührs, W., Bacigalupo, G., Kadenbach, B. et al. Der Einfluss von Chlorpromazin auf die oxydative Phosphorylierung von Tumormitochondrien. Experientia 15, 376–377 (1959). https://doi.org/10.1007/BF02158960

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  • DOI: https://doi.org/10.1007/BF02158960

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