Eine neue Umlagerungsreaktion und ein neues Prinzip zum Aufbau von Peptidketten

Summary

In a series of model reactions, it is shown that residues ofα-aminoacids may be inserted by a particular rearrangement into certain carboxyl or carbonylamido groups. Repeated insertion results in the formation of a peptide derivative. It is concluded that natural peptides or proteins must not necessarily be formed by head to tail combination of aminoacids. Other implications of the new principle are discussed.