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Biogenetic relationships between coumarins, flavonoids, isoflavonoids, and rotenoids

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Zusammenfassung

Einleitend wird auf die bisherigen Ergebnisse über die Biogenese der Flavonoide, der Zimtsäurederivate und der Cumarine eingegangen. Für die Herkunft der C9-Einheit in diesen Verbindungen ergeben sich enge biogenetische Zusammenhänge. Die unter Phenylwanderung verlaufende Biogenese der Isoflavone wird eingehend diskutiert. Die Bildung der Isoflavone und der Flavonoide verläuft sehr wahrscheinlich über eng verwandte Vorstufen. Es wird dann ausführlich auf die strukturellen Beziehungen zwischen Isoflavonen und Rotenoiden eingegangen und ein Biosyntheseweg für die Rotenoide vorgeschlagen, welcher zu der richtigen Oxydationsstufe des Heterocyclus führt. Als zentrale Zwischenstufe für die Biogenese der Flavonoide, der Isoflavone und der Rotenoide kann ein Chalkon angesehen werden. Abschliessend werden die biogenetischen Beziehungen zu den 4-Arylchromanen behandelt.

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  1. Chemisches Laboratorium der Universität, Freiburg i. Br., Germany

    H. Grisebach

  2. University of Bristol, England

    W. D. Ollis

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We should like to thank ProfessorL. Ruzicka for his advice and detailed criticism of this manuscript.

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Grisebach, H., Ollis, W.D. Biogenetic relationships between coumarins, flavonoids, isoflavonoids, and rotenoids. Experientia 17, 4–12 (1961). https://doi.org/10.1007/BF02157921

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