Zusammenfassung
Die Synthese von 6 Polypeptiden aus den im Bradykinin vorkommenden Aminosäuren wird beschrieben. Das Nonapeptid H-l-Arg-l-Pro-l-Pro-Gly-l-Phe-l-Ser-l-Pro-l-Phe-l-Arg-OH zeigte hohe Bradykinin-ähnliche Wirksamkeit in verschiedenen biologischen Testen.
Article PDF
Literatur
M. Rocha eSilva,Biochemistry and Pharmacology of Bradykinin, inM. Schachter,Polypeptides which Affect Smooth Muscles and Blood Vessels (Pergamon Press, Oxford-London-New York-Paris 1960).
D. F. Elliott, G. P. Lewis, andE. W. Horton, Biochem. J.74, 15 P (1960).
D. F. Elliott, E. W. Horton, andG. P. Lewis, J. Physiol.150, 6 P (1960).
D. F. Elliott, paper read to the Biochemical Society (London) on April 8, 1960. We thank Dr.Elliott for kindly giving us some of his results before communication.
H. O. J. Collier, J. A. Holgate, M. Schachter, andP. G. Shorley, J. Physiol.149, 54 P (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Boissonnas, R.A., Guttmann, S., Jaquenoud, P.A. et al. Synthesis and biological activity of peptides related to bradykinin. Experientia 16, 326 (1960). https://doi.org/10.1007/BF02157779
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02157779