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Konfiguration und pharmakologische Aktivität bei 1-phenäthylsubstituierten 1,2,3,4-Tetrahydroisochinolinen

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Summary

The absolute configuration of four pharmacologically active tetrahydroisoquinolines has been determined. It was shown that both the levorotatory antipodes of I, II and III and the dextrorotatory enantiomer of IV possessR-configuration at the asymmetric center.

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References

  1. A. Brossi, H. Besendorf, B. Pellmont, M. Walter undO. Schnider, Helv. chim. Acta43, 1459 (1960).

    Article  CAS  Google Scholar 

  2. H. Besendorf, B. Pellmont, H. P. Bächtold, K. Reber undA. Studer, Exper.18, 446 (1962).

    CAS  Google Scholar 

  3. Handelsname «Versidyne».

  4. M. Walter, H. Besendorf undO. Schnider, Helv. chim. Acta46, 1127 (1963).

    Article  Google Scholar 

  5. Wärmereiztest an der Maus nachF. Gross, Helv. physiol. pharmacol. Acta5, C 31 (1947).

  6. Elektrische Reizung des N. laryngeus sup. der Katze nachR. Domenjoz, Arch. exp. Path. Pharmak.215, 19 (1952).

    CAS  Google Scholar 

  7. A. Rheiner Jr. undA. Brossi, Helv. chim. Acta45, 2590 (1962).

    Article  CAS  Google Scholar 

  8. A. Brossi undF. Burkhardt, Helv. chim. Acta44, 1558 (1961).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Chemische Forschungsabteilung der F. Hoffmann-La Roche & Co. AG, Basel, Schweiz

    A. Rheiner Jr. & A. Brossi

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  1. A. Rheiner Jr.
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  2. A. Brossi
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Rheiner, A., Brossi, A. Konfiguration und pharmakologische Aktivität bei 1-phenäthylsubstituierten 1,2,3,4-Tetrahydroisochinolinen. Experientia 20, 488–489 (1964). https://doi.org/10.1007/BF02154063

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  • DOI: https://doi.org/10.1007/BF02154063

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