Summary
In contrast to the inhibitory effect exercised by Cortisone upon connective and lymphatic tissue, of the rat it produces an increase in the compensatory hypertrophy of the remaining kidney after removal of the other one when given in doses of 1 and 5 (2.5) mg every second day. 11-Desoxycorticosterone or 11-descoxy-17-hydroxy-corticosterone (Compound S) have no influence on the development of compensatory renal hypertrophy. Cortisone does not diminish the hyperplasia of the thyroid gland after treatment with methyl-thiouracil or the growth of the seminal vesicles which occurs after treatment with testosterone.
References
T. F. Dougherty undA. White, Proc. Soc. Exp. Biol. and Med.53, 132 (1943).
J. D. Feldman, Endocrinology46, 552 (1950).
R. S. Mach undP. Ducommun, La Semaine des Hôpitaux26, 3170 (1950).
R. Meier, W. Schuler undP. Desaulles, Exper.6, 469 (1950).
Ch. Ragan, E. L. Howes, Ch. M. Plotz, K. Meyer undJ. W. Blunt, Proc. Soc. Exp. Biol. and Med.72, 718 (1939).
P. Ducommun, Acta Endocrinol.4, 343 (1950).
C. A. Winter, R. H. Silber undH. C. Stoerk, Endocrinol.47, 60 (1950).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gross, F., Meier, R. Die Beeinflussung der kompensatorischen Nierenhypertrophie durch Cortisone und andere Nebennierenrindensteroide. Experientia 7, 74–75 (1951). https://doi.org/10.1007/BF02153837
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02153837