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Der Einfluss vonα-Methyl-Dopa auf die Tyraminwirkung an mit Reserpin vorbehandelten Katzen

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Summary

In cats pretreated with reserpine, the action of tyramine on the blood pressure is markedly enhanced 30–90 min after infusion of 500 mgl-α-methyl-dopa, but not after the same amount of the dextro isomer. In normal catsl-α-methyl-dopa has no influence on this action of tyramine. 1–2 h after the infusion ofα-methyl-dopa, an increase of the response to tyramine could also be observed in experiments on the nictating membrane of reserpine pretreated cats. The effects of preganglionic electrical stimulation of the cervical sympathetic nerve remained unchanged.

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Authors and Affiliations

  1. Medizinische Forschungslaboratorien der Farbenfabriken Bayer AG, Wuppertal-Elberfeld, Deutschland

    G. Kroneberg & K. Stoepel

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  1. G. Kroneberg
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  2. K. Stoepel
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Kroneberg, G., Stoepel, K. Der Einfluss vonα-Methyl-Dopa auf die Tyraminwirkung an mit Reserpin vorbehandelten Katzen. Experientia 19, 252–253 (1963). https://doi.org/10.1007/BF02151364

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  • DOI: https://doi.org/10.1007/BF02151364

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