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Two types of 5-hydroxytryptamine release from isolated blood platelets

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Zusammenfassung

Nach Einwirkung von Reserpin auf gewaschene, isolierte Thrombocyten werden neben 5-Hydroxytryptamin, 5-Hydroxyindolessigsäure und eine Substanz mit den Characteristika von N-Acetyl-5-hydroxytryptamin im Inkubationsmedium (modifizierte Tyrodelösung) gefunden. Das Phenyläthylaminderivat Ro 4-6861 setzt 5-Hydroxytryptamin ohne Bildung dieser Metabolite frei.

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Literatur

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Authors and Affiliations

  1. Medizinische Forschungsabteilung, F. Hoffmann-La Roche & Co. AG, Basel, Switzerland

    G. Bartholini & A. Pletscher

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  1. G. Bartholini
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  2. A. Pletscher
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Bartholini, G., Pletscher, A. Two types of 5-hydroxytryptamine release from isolated blood platelets. Experientia 20, 376–378 (1964). https://doi.org/10.1007/BF02147970

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