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The effect of reserpine upon gastrointestinal serotonin in the sprague-dawley rat

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Zusammenfassung

Der Serotoningehalt der Schleimhaut von 14 gastrointestinalen Geweben von Sprague-Dawley Rattenmännchen und -weibchen wurde nach i.p. Injektion von Reserpin spektrophotofluorimetrisch gemessen. Die Verteilung von Serotonin im Magendarmkanal 4 und 16 h nach der Reserpininjektion zeigte, dass Magengewebe und Kolongewebe nach 16 h mehr entleert waren als nach 4 h, während Dünndarm und Appendix nach 4 h mehr entleert waren als nach 16 h.

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Authors and Affiliations

  1. Department of Pharmacology and Experimental Therapeutics, UCLA School of Medicine, 90024, Los Angeles, California, USA

    J. H. Thompson & L. B. Campbell

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  1. J. H. Thompson
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  2. L. B. Campbell
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Additional information

This research was supported by U.S.P.H.S. grant No. AM 07909, toJ. H. Thompson.

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Thompson, J.H., Campbell, L.B. The effect of reserpine upon gastrointestinal serotonin in the sprague-dawley rat. Experientia 23, 826–828 (1967). https://doi.org/10.1007/BF02146868

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