Skip to main content
SpringerLink
Log in

Effect of cardiac catecholamine depletion through sympathectomy on spontaneous ventricular fibrillation during induced hypothermia in cats

  • Specialia
  • Physiologica
  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

Versuche mit Katzen haben gezeigt, dass Hypothermie in einer Reduzierung des Noradrenalingehaltes im Herzen resultiert (zentrale Aktivierung). Der Versuch, den Noradrenalingehalt im Herzen durch Sympathektomie 2 oder 3 Tage vor Unterkühlung zu reduzieren, ergibt aber keinen signifikanten Schutz gegen spontanes Ventrikelflimmern. Dieses Verhalten beruht wahrscheinlich auf der schnellen Entwicklung der Empfindlichkeitssteigerung des Myokards gegenüber Katecholaminen und besonders Noradrenalin, das von adrenergen Herznerven freigesetzt wird (bei unvollständiger Denervierung).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. K. C. Nielsen andCh. Owman, Life Sci.7, 159 (1968).

    Article  CAS  Google Scholar 

  2. K. C. Nielsen andCh. Owman, Experientia23, 203 (1967).

    Article  CAS  Google Scholar 

  3. K. C. Nielsen andCh. Owman, Circulation Res.21, 45 (1967).

    Article  CAS  Google Scholar 

  4. K. C. Nielsen andCh. Owman, Archs int. Pharmacodyn. Thér., in press (1968).

  5. K. C. Nielsen andCh. Owman, Life Sci.5, 1611 (1966).

    Article  CAS  Google Scholar 

  6. S. Z. Langer, P. R. Draskoczy andU. Trendelenburg, J. Pharmac. exp. Ther.157, 255 (1967).

    CAS  Google Scholar 

  7. K. C. Nielsen, Ch. Owman andM. Santini, Brain Res.12, 1 (1969).

    Article  CAS  Google Scholar 

  8. K. C. Nielsen andCh. Owman, Acta physiol. scand., in press (1968).

  9. Å. Bertler, A. Carlsson, E. Rosengren andB. Waldeck, Kungl. Fysiogr. Sällsk. Lund Förh.28, 121 (1958).

    CAS  Google Scholar 

  10. J. Häggendal, Acta physiol. scand.59, 242 (1963).

    Article  Google Scholar 

  11. P. Somani andB. K. B. Lum, J. Pharmac. exp. Ther.147, 194 (1965).

    CAS  Google Scholar 

  12. M. Goldstein andK. Nakajima, Life Sci.5, 175 (1966).

    Article  CAS  Google Scholar 

  13. M. Ide, Tohoku J. exp. Med.73, 70 (1960).

    Article  CAS  Google Scholar 

  14. C. R. Bennett, H. H. Smookler andJ. P. Buckley, J. Pharmac. exp. Ther.159, 115 (1968).

    CAS  Google Scholar 

  15. T. G. Brown andM. V. Cotten, Fedn Proc. Fedn Am. Socs exp. Biol.15, 405 (1956).

    Google Scholar 

  16. W. Holobut, Acta physiol. hung.29, 383 (1966).

    Google Scholar 

  17. B. Falck andCh. Owman, Acta Univ. Lund. II7, 1 (1965).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Neurosurgical Clinic A, University Hospital of Lund, Institute of Anatomy and Histology, Department of Pharmacology, Lund University, 223 62, Lund, Sweden

    K. C. Nielsen, Ch. Owman & E. Rosengren

  2. Department of Neurological Surgery, New York University Medical School, New York, N.Y., USA

    K. C. Nielsen, Ch. Owman & E. Rosengren

Authors
  1. K. C. Nielsen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ch. Owman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Rosengren
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported by grants from the Association for the Aid of Crippled Children, New York; and from Anna-Lisa and Sven Eric Lundgren's Foundation.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nielsen, K.C., Owman, C. & Rosengren, E. Effect of cardiac catecholamine depletion through sympathectomy on spontaneous ventricular fibrillation during induced hypothermia in cats. Experientia 24, 1215–1217 (1968). https://doi.org/10.1007/BF02146629

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02146629

Keywords

Search

Navigation