Summary
Techniques are described for the isolation of nuclei from animals cells and for the determination of the desoxyribonucleic acid content for each nucleus. These techniques have already been used in order to study a few mammalian species. From the first results (especially in calf, ox and bull), it seems to appear that the nucleus of the somatic cells contains constantly the same amount of desoxyribonucleic acid, whatever tissue and animal we studied within the same species; and this amount is just the double of that of the haploid cells (spermatozoa) in the same animal. This result constitutes a strong argument, from the analytical point of view, for the theory according to which the desoxyribonucleic acid is considered to be the substrate of the hereditary characters of the species.
Literatur
Voir spécialement l'article récent deJ. N. Davidson (Cold Spring Harbor Symp. Quant. Biol.12, 50 [1947]) qui résume les résultats de ses devanciers et donne la bibliographie de la question.
Voir notre note préliminaire:A. Boivin, R. Vendrely etC. Vendrely C. R. Acad. Sci.226, 1061 (1948).
G. Crossmon, Science85, 250 (1937).
C. A. Stoneburg, J. Biol. Chem.129, 189 (1939).
A. Marshak, J. Gen. Physiol.25, 275 (1941).
M. Laskowski, Proc. Soc. Exp. Biol. Med.49, 354 (1942).
A. Lazarow, J. Biol. Chem.140, 75 (1941).
A. Dounce, J. Biol. Chem.147, 685 (1943) et151, 235 (1943).
W. C. Schneider, J. Biol. Chem.161, 293 (1945).
R. Vendrely etR. Sarciron, Bull. Soc. Chim. biol.26, 214 (1944).
Z. Dische, Mikrochemie8, 4 (1930).
H. v. Euler etL. Hahn, Svenks kem. Tidskr.58, 251 (1946).
G. Schmidt etS. J. Thannhauser, J. Biol. Chem.161, 83 (1945).
A. E. Mirsky etA. W. Pollister, Biol. Symp.10, 247 (1943).
A. E. Mirsky, Adv. Enzymol.3, 1 (1943).
A. W. Pollister etA. E. Mirsky, J. Gen. Physiol.30, 101 (1946).
A. E. Mirsky etA. W. Pollister, J. Gen. Physiol.30, 117 (1946).
Ch. A. Zittle etB. Zitin, J. Biol. Chem.144, 99 (1942).
A. Boivin, A. Delaunay, R. Vendrely etY. Lehoult, Exper.1, 334 (1945);2, 139 (1946); CR. Acad. Sci.221, 718 (1945).
A. Boivin, R. Vendrely etY. Lehoult, CR. Acad. Sci.221, 646 (1945).
A. Boivin etR. Vendrely, Exper.3, 32 (1947).
A. Boivin, Cold Spring Harbor Symp. Quant. Biol.12, 7 (1947).
Voir par exemple:A. Boivin, R. Tulasne etR. Vendrely, CR. Acad. Sci.225, 703 (1947).
A. Boivin, R. Vendrely etR. Tulasne, Arch. Sci. Physiol.1, 35 (1947).
A. Boivin, R. Tulasne, R. Vendrely etR. Minck, Arch. Sci. Physiol.1, 307 (1947).
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Vendrely, R., Vendrely, C. La teneur du noyau cellulaire en acide désoxyribonucléique à travers les organes, les individus et les espèces animales. Experientia 4, 434–436 (1948). https://doi.org/10.1007/BF02144998
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DOI: https://doi.org/10.1007/BF02144998