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Effect of 5-azacytidine on developing mouse embryo

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  • Anatomica. Histologica. Carcinologica
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Zusammenfassung

5-Azacytidin wurde trächtigen Mäusen am 4.–6. und 11.–13. Tag verabreicht. Bei der ersten Gruppe zeigte sich eine völlige Resorption der Feutusse, während in der zweiten Gruppe hauptsächlich die Leber und das Nervengewebe geschädigt waren. In der ependymalen Zone werden die in Teilung befindlichen Zellen in der Metaphase gestoppt und unterliegen einer pyknotischen Degeneration.

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Authors and Affiliations

  1. Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Praha, Czechoslovakia

    M. Seifertová, J. Veselý & F. Šorm

Authors
  1. M. Seifertová
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  2. J. Veselý
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  3. F. Šorm
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Seifertová, M., Veselý, J. & Šorm, F. Effect of 5-azacytidine on developing mouse embryo. Experientia 24, 487–488 (1968). https://doi.org/10.1007/BF02144408

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  • DOI: https://doi.org/10.1007/BF02144408

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