Summary
It has been shown that reserpine and guanethidine deplete granules containing catecholamine in sympathetic nerve endings of both the pineal gland and the vas deferens. This effect is blocked by iproniazid. Bretylium is not able to deplete these granules but it modifies their aspect. It has also been observed that granules of the adrenal medulla are depleted less easily than those of sympathetic nerve endings.
References
A. Pellegrino de Iraldi etE. De Robertis, Exper.17, 122 (1961).
A. Pellegrino de Iraldi etE. De Robertis, Int. J. Neuropharmacol.2, 231 (1963).
N. C. R. Merrillees, G. Burnstock etM. Holman, J. Cell Biol.19, 529 (1963).
K. C. Richardson, Biochem. Pharmacol.12, 11 (1963).
P. Lundborg, Exper.19, 479 (1963).
U. S. von Euler etF. Lishajko, Acta physiol. scand.51, 193 (1961).
U. S. von Euler etF. Lishajko, Acta physiol. scand.57, 468 (1963).
G. Herting, Nature192, 172 (1961).
D. E. Wolfe, L. T. Potter, K. Richardson etJ. Axelrod, Science138, 440 (1962).
E. De Robertis etV. Ferreira, J. Biophys. Biochem. Cytol.3, 611 (1957).
J. H. Burn etM. J. Rand, Brit. Med. J.1, 394 (1959).
J. H. Burn, Bull. Johns Hopkins Hosp.112, 167 (1963).
E. D. De Robertis etD. D. Sabatini, Fed. Proc.19, Suppl. 90 (1960).
B. B. Brodie etM. A. Beaven, Med. exp.8, 320 (1963).
A. Ryter etE. Kellemberger, J. ultr. Res.2, 800 (1958).
F. Clementi etG. P. Zocche, J. Cell Biol.17, 587 (1963).
B. Callingham etM. Mann, Brit. J. Pharmacol.18, 138 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Clementi, F. Modifications ultrastructurelles provoquées par quelques médicaments sur les terminaisons nerveuses adrénergiques et sur la médullaire surrénale. Experientia 21, 171–176 (1965). https://doi.org/10.1007/BF02142003
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02142003