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Effect of win 18501-2 on the content of catecholamines and the number of catecholamine-containing granules in the rabbit hypothalamus

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Zusammenfassung

Der Hypothalamus von Kaninchen wurde nach Win 18501-2-Injektion biochemisch und elektronenmikroskopisch untersucht. Die Behandlung erzeugte auffallende Veränderungen im Noradrenalingehalt und in der Anzahl der Katecholamine enthaltenden granulierenden Vesiculae im Hypothalamus. Die Resultate scheinen zu zeigen, dass diese charakteristischen Vesiculae nur Noradrenalin enthalten und dass die Sedation des Kaninchens nach der Injektion von Win 18501-2 auf der Verminderung des Noradrenalins und der charakteristischen Vesiculae beruht.

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Authors and Affiliations

  1. Department of Pharmacology, Institute for Higher Nervous Activity, Osaka University Medical School, Osaka, Japan

    M. Matsuoka & R. Imaizumi

  2. Department of Neuroanatomy, Institute for Higher Nervous Activity, Osaka University Medical School, Osaka, Japan

    S. Ishii & N. Shimizu

Authors
  1. M. Matsuoka
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  2. S. Ishii
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  3. N. Shimizu
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  4. R. Imaizumi
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Matsuoka, M., Ishii, S., Shimizu, N. et al. Effect of win 18501-2 on the content of catecholamines and the number of catecholamine-containing granules in the rabbit hypothalamus. Experientia 21, 121–123 (1965). https://doi.org/10.1007/BF02141966

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  • DOI: https://doi.org/10.1007/BF02141966

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