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The generation of dense granules within cultured human retinal pigment epithelial cells at senescence

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Abstract

Human retinal pigment epithelial cells routinely lose all forms of pigmentary inclusion when cultured. We report the repigmentation of a senescent population of cells. The pigmented inclusions were found to be neither melanin or lipofuscin but some form of dense membranous lamellae.

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Boulton, M., Marshall, J. & Wong, H.C. The generation of dense granules within cultured human retinal pigment epithelial cells at senescence. Graefe's Arch Clin Exp Ophthalmol 224, 106–109 (1986). https://doi.org/10.1007/BF02141479

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  • DOI: https://doi.org/10.1007/BF02141479

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