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Autoradiographic demonstration of uptake and accumulation of3H-6-hydroxydopamine in adrenergic nerves

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Zusammenfassung

Die Regenbogenhaut der Maus wurde in einer physiologischen Pufferlösung mit radioaktivem 6-Hydroxydopamin (3H-6-OH-DA) inkubiert. Mit Hilfe autoradiographischer und fluoreszenz-histochemischer Untersuchungen konnte gezeigt werden, dass3H-6-OH-DA in die adrenergischen Nervenfasern der Regenbogenhaut aufgenommen und gespeichert wird. Dieser Befund bringt die direkte Erklärung der durch 6-Hydroxydopamin induzierten Degeneration der adrenergen Fasern.

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Authors and Affiliations

  1. Department of Histology, Karolinska Intitutet, S-10401, Stockholm, Sweden

    Å. Ljungdahl, T. Hökfelt, G. Jonsson & Ch. Sachs

Authors
  1. Å. Ljungdahl
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  2. T. Hökfelt
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  3. G. Jonsson
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  4. Ch. Sachs
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Ljungdahl, Å., Hökfelt, T., Jonsson, G. et al. Autoradiographic demonstration of uptake and accumulation of3H-6-hydroxydopamine in adrenergic nerves. Experientia 27, 297–299 (1971). https://doi.org/10.1007/BF02138157

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