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Medicagenic acid, the factor responsible for hemolytic activity of lucerne saponins

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  • Mineralogica, Geophysica, Oceanographica
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Zusammenfassung

Die aus Wurzeln von Luzerne isolierten Saponine wirken stärker hämolytisch als diejenigen in den grünen Teilen dieser Pflanze. Die hämolytisch wirksameren Saponine sind reicher an Medicagensäure und es wird angenommen, dass diese für die hämolytische Wirkung der Saponine verantwortlich ist. Die Anwesenheit von 2 Carboxylgruppen in der Medicagensäure scheint für ihre hämolytische Wirkung von ausschlaggebender Bedeutung zu sein, da der Dimethylester dieser Säure nicht mehr hämolytisch wirkt.

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Authors and Affiliations

  1. Faculty of Agriculture, The Hebrew University of Jerusalem, P.O. Box 12, Rehovot, Israel

    B. Gestetner, S. Shany & Y. Assa

Authors
  1. B. Gestetner
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  2. S. Shany
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  3. Y. Assa
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Additional information

This work was supported by Grant No. FG-Is-246 from the U.S. Department of Agriculture.

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Gestetner, B., Shany, S. & Assa, Y. Medicagenic acid, the factor responsible for hemolytic activity of lucerne saponins. Experientia 27, 40–41 (1971). https://doi.org/10.1007/BF02137729

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  • DOI: https://doi.org/10.1007/BF02137729

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