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The distribution of glucose and methyl-glucose between the liver and plasma in normal and insulin injected rats

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Zusammenfassung

Es wurde gefunden, dass 3-Methyl-Glukose (MEG) sich in 85% der gesamten Gewebeflüssigkeit der Rattenleber löst. Ist Glukose in gleicher Plasmamenge enthalten, so ist die berechnete Konzentration in der Leberzellflüssigkeit doppelt so hoch. Bei Insulinhypoglykämie stieg dieses Verhältnis weiter an, ohne aber eine Veränderung im Verteilungsvolumen von MEG zu ergeben. Die Leberzellmembran scheint die Penetration der Glukose aus der Zelle zu verzögern.

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Literatur

  1. K. F. Gey, Biochem. J.64, 145 (1956).

    Article  CAS  Google Scholar 

  2. G. Hetenyi Jr. andG. S. Arbus, J. gen. Physiol.45, 1049 (1962).

    Article  CAS  Google Scholar 

  3. R. Steele, Ergebn. Physiol57, 91 (1966).

    Article  CAS  Google Scholar 

  4. D. S. Riggs,The Mathematical Approach to Physiological Problems (William and Wilkins Co., Baltimore 1963).

    Google Scholar 

  5. A. Wollenberger, O. Ristau andG. Schoffa, Pflügers Arch. ges. Physiol.270, 399 (1960).

    Article  CAS  Google Scholar 

  6. H. E. Morgan, P. J. Randle andD. M. Regen, Biochem. J.73, 573 (1959).

    Article  CAS  Google Scholar 

  7. A. S. G. Hugget andD. A. Nixon, Biochem. J.66, 12P (1957).

  8. P. Berthet, P. Jacques, H. G. Hers andC. de Duve, Biochim. biophys. Acta20, 190 (1956).

    Article  CAS  Google Scholar 

  9. T. Z. Csaky andJ. E. Glenn, Proc. Soc. exp. Biol. Med.98, 400 (1958).

    Article  CAS  Google Scholar 

  10. H. T. Narahara andP. Özand, J. biol. Chem.238, 40 (1963).

    Article  CAS  Google Scholar 

  11. J. F. Manery andA. B. Hastings, J. biol. Chem.127, 657 (1939).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Physiology, University of Toronto, Toronto 2, Canada

    G. Hetenyi Jr. & D. Studney

  2. The Charles H. Best Institute, Toronto 2, Canada

    G. Hetenyi Jr. & D. Studney

Authors
  1. G. Hetenyi Jr.
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  2. D. Studney
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Additional information

The financial support of The Medical Research Council of Canada and the Banting Foundations as well as the skilled technical help of Mrs.S. Waterfield is gratefully acknowledged.

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Hetenyi, G., Studney, D. The distribution of glucose and methyl-glucose between the liver and plasma in normal and insulin injected rats. Experientia 23, 219–220 (1967). https://doi.org/10.1007/BF02136299

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