Summary
Between 1978 and 1983 1240 singleton placentas were examined macroscopically and histologically. In 82 cases (6.6%) a “chronic placentitis” was diagnosed. The pathognomonic inflammatory foci were localized within the placental villi. The vast majority showed mixtures of both fibrohistiocytes and lymphoid cells, which were occasionally interspersed with plasma-cells. The clinical data relating to 67 placentas were correlated retrospectively with the degree of inflammation 46 showed mild and 21 moderate to severe chronic placentitis. In both of these groups the proportion of preterm deliveries and cases with preeclampsia was equally high. With increasing serverity of chronic placentitis, however, there was a significant reduction in weight and size of both, placenta and infant, and the incidence of perinatal asphyxia was significantly raised.
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References
Altshuler G, Russel P (1975) The human placental villitides: A review of chronic intrauterine infection. Curr Top Pathol 60: 63–112
Altshuler G, Mc Adams AJ (1972) The role of the placenta in the fetal and perinatal pathology. Am J Obstet Gynecol 616: 616–631
Becker V (1981) Morphologische Plazenta-Diagnostik. In: Becker V, Schieber ThH, Kubli F (eds) Die Plazenta des Menschen. G. Thieme-Verlag, Stuttgart, New York, pp 499–516
Blanc WA (1980) Pathology of the placenta and cord in ascending and in hematogenous infection. Ciba Found Symp 77: 1738
Blanc WA (1981) Pathology of the placenta membranes and nutricical cord in bacterial, fungal and viral infections in man. Monogr Pathol 22: 67–132
Benirschke K (1976) Diseases of the placenta. In: Gluck L (ed) Modern perinatal medicine. Year Book, Med Publ, Chicago, pp 99–109
Bjøro K, Myhre E (1984) The role of chronic non-specific inflammatory lesions of the placenta in intra-uterine growth retardation. Acta Pathol Microbiol Immunol Scand [A] 92: 133–137
Dische MR, Quinn PA, Czegledy-Nagy E, Sturgess JM (1979) Genital mycoplasma infection. I. Intrauterine infection: Pathologic study of the fetus and the placenta. Am J Clin Pathol 72: 167–174
Dollmann, A, Schmitz-Moormann P (1972) Rekurrierende Plazentainsuffizienz durch villöse Plazentitis mit extremer fetaler Hypotrophie. Geburtshilfe Frauenheilkd 32: 795–801
Dollmann A (1973) The small-for-date infant and its placenta: a clinical-pathological study. In: Perinatal medicine. Huber Verlag, Bern, p 288
Fox H (1978) Pathology of the placenta. Saunders Co, London, Philadelphia, Toronto
Gershon R, Strauss L (1961) Structural changes in human placentas associated with fetal inanition or growth arrest (“placental insufficiency syndrome”). Am J Dis Child 102: 645–646
Gille J (1979) Die Untersuchung der Plazenta. Med Klin 74: 1380–1390
Homberger CP, Chauhan P, Blanc WA (1971) Lymphoplasmacytic placentitis, fetal infection and placental immunglobulin synthesis. Abstract, Pediatric Pathology Meeting, International Acedemy of Pathology, Montreal
Kubli F, Wernicke K (1981) Plazentainsuffizienz. In: Becker V, Schiebler ThH, Kubli K (eds) Die Plazenta des Menschen. G. Thieme Verlag, Stuttgart, New York, pp 395–477
Kyank H, Herre HD, Kruse HJ, Löscher H, Ketscher KD, Pleese R (1975) Ergebnisse einer Normalwerterhebung Neugeborener in der DDR. Zentralbl Gynäkol 97: 129–137
Labarrere C (1982) Chronic villitis of unknown etiology in small-for-gestational-age infants. Placenta 3: 309–317
Laga EM, Driscoll SG, Munro HN (1972) Comparison of placentas from two socioeconomic groups. I. Morphometry. Pediatrics 50: 24–32
Romeis B (1968) Mikroskopische Technik, 16th Edn. Oldenbourg Verlag, München, Wien
Russel P (1979) Inflammatory lesions of the human placenta. II. Villitis of unknown etiology in perspective. Am I Diagn Gynecol Obstet 1: 339–346
Russel P (1980) Inflammatory lesions of the human placenta. III. The histopathology of villitis of unknown aetiology. Placenta 1: 227–244
Sachs L (1968) Statistische Auswertungsmethoden. Springer-Verlag, Berlin, Heidelberg, New York
Sandstedt B (1979) The placenta and low birth weight. Curr Top Pathol 66: 1–55
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Rüschoff, J., Böger, A. & Zwiens, G. Chronic placentitis — a clinicopathological study. Arch. Gynecol. 237, 19–25 (1985). https://doi.org/10.1007/BF02133947
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DOI: https://doi.org/10.1007/BF02133947