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Adsorption of influenza virus to charged groups on natural and artificial surfaces

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Abstract

Adsorption properties for the fowl plague virus have been tested with red blood cells and with negatively or positively charged compounds bound to agarose beads. It was found, that all anions or cations tested could adsorb the virus effectively, provided that the charges are sufficiently accessible to the virus. The results showed that electrostatic attraction is the principal functioning mechanism in the adsorption of influenza virus.

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References

  1. Allison, A. C., Valentine, R. C.: Virus particle adsorption. III. Adsorption of viruses by cell monolayers and effects of some variables on adsorption. Biochim. biophys. Acta (Amst.)40, 400–410 (1960)

    Article  Google Scholar 

  2. Andrews, C. H., Bang, F. B., Burnet, F. M.: A short description of the myxovirus group (influenza and related viruses). Virology1, 176–184 (1955)

    Article  PubMed  Google Scholar 

  3. Bangham, A. D., Pethica, B. A., Seaman, G. V. F.: The charged groups at the interface of some blood cells. Biochem. J.69, 12–18 (1958)

    PubMed  Google Scholar 

  4. Chucholowius, H.-W., Rott, R.: A new method for purification of myxoviruses by zonal centrifugation with two different sucrose density gradients. Proc. Soc. exp. biol. (N.Y.)140, 245–247 (1972)

    Google Scholar 

  5. Cuatreacasas, P.: Protein purification by affinity chromatography. J. biol. Chem.245, 3059–3065 (1970)

    PubMed  Google Scholar 

  6. Fazekas de St. Groth, S., Graham, D.: Modification of virus receptors by metaperiodate: infection through modified receptors. Aust. J. exp. Biol. med. Sci.27, 83–94 (1949)

    Google Scholar 

  7. Hirst, G. K.: The quantitative determination of influenza virus and antibodies by means of red cell agglutination. J. exp. Med.75, 49–65 (1942)

    Article  Google Scholar 

  8. Horton, D., Lineback, D. R. In: Methods in carbohydrate chemistry V, pp. 403–406; N-Deacetylation, chitosan from chitin Edited by R. L. Whistler. New York-London: Academic Press 1965

    Google Scholar 

  9. Huang, R. T. C., Rott, R., Klenk, H.-D.: On the receptor of influenza viruses. 1. Artificial receptor for influenza virus. Z. Naturforsch.28c, 342–345 (1973)

    Google Scholar 

  10. Levine, S., Sagik, B. P.: The interaction of Newcastle disease virus (NDV) with chick embryo tissue culture cells: Attachment and growth. Virology2, 57–68 (1956)

    Article  PubMed  Google Scholar 

  11. Miller, G. L., Lauffer, M. A., Stanley, W. M.: Electrophoretic studies on PR8 influenza virus. J. exp. Med.80, 549–559 (1944)

    Article  Google Scholar 

  12. Porath, J., Axen, R., Ernback, S.: Chemical coupling of protein to agarose. Nature (Lond.)215, 1491–1492 (1967)

    Google Scholar 

  13. Sagik, B. P., Levine, S.: The interaction of newcastle disease virus (NDV) with chicken erythrocytes: Attachment, elution, and hemolysis. Virology3, 401–416 (1957)

    Article  PubMed  Google Scholar 

  14. Valentine, R. C., Allison, A. C.: Virus particle adsorption. 1. Theory of adsorption and experiments on the attachment of particles to non-biological surfaces. Biochim. biophys. Acta (Amst.)34, 10–23 (1959).

    Article  Google Scholar 

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  1. Institut für Virologie, Justus Liebig-Universität, Gie\en

    R. T. C. Huang

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Huang, R.T.C. Adsorption of influenza virus to charged groups on natural and artificial surfaces. Med Microbiol Immunol 159, 129–135 (1974). https://doi.org/10.1007/BF02123725

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  • DOI: https://doi.org/10.1007/BF02123725

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